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361 results

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Page 1
Covalent targeting of splicing in T cells.
Scott KA, Kojima H, Ropek N, Warren CD, Zhang TL, Hogg SJ, Sanford H, Webster C, Zhang X, Rahman J, Melillo B, Cravatt BF, Lyu J, Abdel-Wahab O, Vinogradova EV. Scott KA, et al. Among authors: abdel wahab o. Cell Chem Biol. 2024 Nov 22:S2451-9456(24)00445-8. doi: 10.1016/j.chembiol.2024.10.010. Online ahead of print. Cell Chem Biol. 2024. PMID: 39591969
The effect of methylation on the let-7-BCL2L1-BCL2 axis and the potential use of hypomethylating and BH3 mimetic drugs in histiocytic neoplasms.
Salmon-Divon M, Meyuchas R, Shpilberg O, Okon E, Benhamida J, Yabe M, Petrova-Drus K, Zvida-Bloch T, Basood M, Mazor R, Durham BH, Haroche J, Abdel-Wahab O, Diamond EL, Hershkovitz-Rokah O. Salmon-Divon M, et al. Among authors: abdel wahab o. Leukemia. 2024 Nov 8. doi: 10.1038/s41375-024-02459-5. Online ahead of print. Leukemia. 2024. PMID: 39516372 No abstract available.
Phase I First-in-Human Dose Escalation Study of the oral Casein Kinase 1α and Cyclin Dependent Kinase 7/9 inhibitor BTX-A51 in advanced MDS and AML.
Ball B, Xiao W, Borthakur G, Nguyen LXT, Valerio M, Venkatachalam A, Marcucci G, Stein A, Thai DL, Cook D, Chan K, Persaud S, Levine R, Abdel-Wahab O, Ben-Neriah Y, Stein E. Ball B, et al. Among authors: abdel wahab o. Res Sq [Preprint]. 2024 Oct 15:rs.3.rs-4954060. doi: 10.21203/rs.3.rs-4954060/v1. Res Sq. 2024. PMID: 39483885 Free PMC article. Preprint.
Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes-Recommendations From the International Consortium for Myelodysplastic Neoplasms/Syndromes (MDS [icMDS]).
Aakash F, Gisriel SD, Zeidan AM, Bennett JM, Bejar R, Bewersdorf JP, Borate UM, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE, Daver NG, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Garcia-Manero G, Gore SD, Greenberg PL, Griffiths EA, Halene S, Hourigan CS, Kim TK, Kim N, Komrokji RS, Kutchroo VK, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Platzbecker U, Della Porta MG, Roboz GJ, Sallman DA, Santini V, Sanz G, Savona MR, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Wei AH, Xie Z, Xu ML, Hasserjian RP, Loghavi S. Aakash F, et al. Among authors: abdel wahab o. Mod Pathol. 2024 Sep 23;37(12):100615. doi: 10.1016/j.modpat.2024.100615. Online ahead of print. Mod Pathol. 2024. PMID: 39322118 Review.
Disruption of cotranscriptional splicing suggests that RBM39 is a therapeutic target in acute lymphoblastic leukemia.
Jin Q, Harris E, Myers JA, Mehmood R, Cotton A, Shirnekhi HK, Baggett DW, Wen JQ, Schild AB, Bhansali RS, Klein J, Narina S, Pieters T, Yoshimi A, Pruett-Miller SM, Kriwacki R, Abdel-Wahab O, Malinge S, Ntziachristos P, Obeng EA, Crispino JD. Jin Q, et al. Among authors: abdel wahab o. Blood. 2024 Sep 24:blood.2024024281. doi: 10.1182/blood.2024024281. Online ahead of print. Blood. 2024. PMID: 39316649 Free article.
Aberrant pre-mRNA processing in cancer.
Biswas J, Boussi L, Stein E, Abdel-Wahab O. Biswas J, et al. Among authors: abdel wahab o. J Exp Med. 2024 Nov 4;221(11):e20230891. doi: 10.1084/jem.20230891. Epub 2024 Sep 24. J Exp Med. 2024. PMID: 39316554 Free PMC article. Review.
Mechanism of neurodegeneration mediated by clonal inflammatory microglia.
Vicario R, Fragkogianni S, Pokrovskii M, Mayer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O, Plu I, Sazdovitch V, Heritier S, Cohen-Aubart F, Shor N, Miyara M, Nguyen-Khac F, Viale A, Idbaih A, Amoura Z, Rosenblum MK, Zhang H, Karnoub ER, Sashittal P, Jakatdar A, Iacobuzio-Donahue CA, Abdel-Wahab O, Tabar V, Socci ND, Elemento O, Diamond EL, Boisson B, Casanova JL, Seilhean D, Haroche J, Donadieu J, Geissmann F. Vicario R, et al. Among authors: abdel wahab o. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605867. doi: 10.1101/2024.07.30.605867. bioRxiv. 2024. PMID: 39131366 Free PMC article. Preprint.
Splicing regulation of DNA repair via CCAR1.
Ai Y, Abdel-Wahab O. Ai Y, et al. Among authors: abdel wahab o. Mol Cell. 2024 Jul 25;84(14):2591-2592. doi: 10.1016/j.molcel.2024.06.012. Mol Cell. 2024. PMID: 39059366
361 results