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Page 1
Dendritome Mapping Unveils Spatial Organization of Striatal D1/D2-Neuron Morphology.
Park CS, Yan M, Zhu M, Akram MA, Foster NN, Bennecke A, Choi C, Marrett K, Moradi K, Zhang JY, Magat G, Nanda S, Vaca R, Wijaya K, Zablan JR, Lee S, Song C, Lara MJ, Louie M, Cong J, Kim Y, Ascoli GA, Langfelder P, Tward D, Dong HW, Yang XW. Park CS, et al. Among authors: langfelder p. bioRxiv [Preprint]. 2024 Oct 24:2024.10.24.619934. doi: 10.1101/2024.10.24.619934. bioRxiv. 2024. PMID: 39484488 Free PMC article. Preprint.
BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice.
Lee CYD, De La Rocha AJ, Inouye K, Langfelder P, Daggett A, Gu X, Jiang LL, Pamonag Z, Vaca RG, Richman J, Kawaguchi R, Gao F, Xu H, Yang XW. Lee CYD, et al. Among authors: langfelder p. bioRxiv [Preprint]. 2023 Aug 5:2023.08.03.551881. doi: 10.1101/2023.08.03.551881. bioRxiv. 2023. PMID: 37577582 Free PMC article. Preprint.
Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice.
Wang N, Zhang S, Langfelder P, Ramanathan L, Plascencia M, Gao F, Vaca R, Gu X, Deng L, Dionisio LE, Prasad BC, Vogt T, Horvath S, Aaronson JS, Rosinski J, Yang XW. Wang N, et al. Among authors: langfelder p. bioRxiv [Preprint]. 2024 Jul 15:2024.07.09.602815. doi: 10.1101/2024.07.09.602815. bioRxiv. 2024. PMID: 39026894 Free PMC article. Preprint.
Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV.
Sehl ME, Breen EC, Shih R, Li F, Zhang J, Langfelder P, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Jamieson BD. Sehl ME, et al. Among authors: langfelder p. Front Bioinform. 2024 May 24;4:1356509. doi: 10.3389/fbinf.2024.1356509. eCollection 2024. Front Bioinform. 2024. PMID: 38855141 Free PMC article.
Erratum: Accelerated aging with HIV begins at the time of initial HIV infection.
Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. Breen EC, et al. Among authors: langfelder p. iScience. 2023 Jul 14;26(8):107381. doi: 10.1016/j.isci.2023.107381. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520728 Free PMC article.
Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.
Wang N, Langfelder P, Stricos M, Ramanathan L, Richman JB, Vaca R, Plascencia M, Gu X, Zhang S, Tamai TK, Zhang L, Gao F, Ouk K, Lu X, Ivanov LV, Vogt TF, Lu QR, Morton AJ, Colwell CS, Aaronson JS, Rosinski J, Horvath S, Yang XW. Wang N, et al. Among authors: langfelder p. Neuron. 2022 Oct 19;110(20):3318-3338.e9. doi: 10.1016/j.neuron.2022.09.028. Neuron. 2022. PMID: 36265442 Free PMC article.
Accelerated aging with HIV begins at the time of initial HIV infection.
Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. Breen EC, et al. Among authors: langfelder p. iScience. 2022 Jun 30;25(7):104488. doi: 10.1016/j.isci.2022.104488. eCollection 2022 Jul 15. iScience. 2022. PMID: 35880029 Free PMC article.
Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, Coppola G, Bates GP, Ranum LPW, Horvath S, Colwell CS, Yang XW. Gu X, et al. Among authors: langfelder p. Neuron. 2022 Apr 6;110(7):1173-1192.e7. doi: 10.1016/j.neuron.2022.01.006. Epub 2022 Feb 2. Neuron. 2022. PMID: 35114102 Free PMC article.
Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner.
Esmaili S, Langfelder P, Belgard TG, Vitale D, Azardaryany MK, Alipour Talesh G, Ramezani-Moghadam M, Ho V, Dvorkin D, Dervish S, Gloss BS, Grønbæk H, Liddle C, George J. Esmaili S, et al. Among authors: langfelder p. Cell Syst. 2021 May 19;12(5):432-445.e7. doi: 10.1016/j.cels.2021.04.004. Epub 2021 May 5. Cell Syst. 2021. PMID: 33957084 Free article.
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Morozko EL, Smith-Geater C, Monteys AM, Pradhan S, Lim RG, Langfelder P, Kachemov M, Kulkarni JA, Zaifman J, Hill A, Stocksdale JT, Cullis PR, Wu J, Ochaba J, Miramontes R, Chakraborty A, Hazra TK, Lau A, St-Cyr S, Orellana I, Kopan L, Wang KQ, Yeung S, Leavitt BR, Reidling JC, Yang XW, Steffan JS, Davidson BL, Sarkar PS, Thompson LM. Morozko EL, et al. Among authors: langfelder p. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2021836118. doi: 10.1073/pnas.2021836118. Proc Natl Acad Sci U S A. 2021. PMID: 33468657 Free PMC article.
47 results