Denny WA - Search Results

1

ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding.

Gong GQ, Masson GR, Lee WJ, Dickson JMJ, Kendall JD, Rathinaswamy MK, Buchanan CM, Middleditch M, Owen BM, Spicer JA, Rewcastle GW, Denny WA, Burke JE, Shepherd PR, Williams RL, Flanagan JU. Gong GQ, et al. Among authors: denny wa. Biochem J. 2024 Dec 4;481(23):1787-1802. doi: 10.1042/BCJ20240479. Biochem J. 2024. PMID: 39485310

2

Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido.

Smaill JB, Rewcastle GW, Loo JA, Greis KD, Chan OH, Reyner EL, Lipka E, Showalter HD, Vincent PW, Elliott WL, Denny WA. Smaill JB, et al. Among authors: denny wa. J Med Chem. 2000 Aug 10;43(16):3199. doi: 10.1021/jm000250q. J Med Chem. 2000. PMID: 10956451 No abstract available.

3

Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate.

Cooper E, Oyagawa CRM, Johnson R, Choi PJ, Foliaki JM, Correia J, Schweder P, Heppner P, Mee E, Turner C, Faull R, Denny WA, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: denny wa. Cell Commun Signal. 2024 Jan 11;22(1):30. doi: 10.1186/s12964-023-01277-z. Cell Commun Signal. 2024. PMID: 38212807 Free PMC article.

4

Retraction: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation.

Datta J, Ghoshal K, Denny WA, Gamage SA, Brooke DG, Phiasivongsa P, Redkar S, Jacob ST. Datta J, et al. Among authors: denny wa. Cancer Res. 2023 Dec 15;83(24):4180. doi: 10.1158/0008-5472.CAN-23-2366. Cancer Res. 2023. PMID: 38098454 Free PMC article. No abstract available.

5

Synthesis and Anti-Mycobacterium tuberculosis Activity of Imidazo[2,1-b][1,3]oxazine Derivatives against Multidrug-Resistant Strains.

Fernandes GFS, Manieri KF, Bonjorno AF, Campos DL, Ribeiro CM, Demarqui FM, Ruiz DAG, Nascimento-Junior NM, Denny WA, Thompson AM, Pavan FR, Dos Santos JL. Fernandes GFS, et al. Among authors: denny wa. ChemMedChem. 2023 Jun 15;18(12):e202300015. doi: 10.1002/cmdc.202300015. Epub 2023 Apr 21. ChemMedChem. 2023. PMID: 37002895

6

Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue.

Cooper E, Woolf Z, Swanson MEV, Correia J, Schweder P, Mee E, Heppner P, Turner C, Faull RLM, Scotter EL, Denny WA, Choi PJ, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: denny wa. Neurooncol Adv. 2022 Oct 14;4(1):vdac166. doi: 10.1093/noajnl/vdac166. eCollection 2022 Jan-Dec. Neurooncol Adv. 2022. PMID: 36382105 Free PMC article.

7

Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug-carrier molecule for the treatment of glioblastoma.

Cooper E, Choi PJ, Hwang K, Nam KM, Kim CY, Shaban T, Schweder P, Mee E, Correia J, Turner C, Faull RLM, Denny WA, Noguchi K, Dragunow M, Jose J, Park TI. Cooper E, et al. Among authors: denny wa. Chem Biol Drug Des. 2023 Mar;101(3):696-716. doi: 10.1111/cbdd.14171. Epub 2022 Nov 29. Chem Biol Drug Des. 2023. PMID: 36323652

8

Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines.

Sutherland HS, Choi PJ, Lu GL, Giddens AC, Tong AST, Franzblau SG, Cooper CB, Palmer BD, Denny WA. Sutherland HS, et al. Among authors: denny wa. Pharmaceuticals (Basel). 2022 Sep 8;15(9):1125. doi: 10.3390/ph15091125. Pharmaceuticals (Basel). 2022. PMID: 36145345 Free PMC article.

9

Tuberculosis Drug Discovery: Challenges and New Horizons.

Fernandes GFS, Thompson AM, Castagnolo D, Denny WA, Dos Santos JL. Fernandes GFS, et al. Among authors: denny wa. J Med Chem. 2022 Jun 9;65(11):7489-7531. doi: 10.1021/acs.jmedchem.2c00227. Epub 2022 May 25. J Med Chem. 2022. PMID: 35612311 Review.

10

Nitroaromatic Hypoxia-Activated Prodrugs for Cancer Therapy.

Denny WA. Denny WA. Pharmaceuticals (Basel). 2022 Feb 2;15(2):187. doi: 10.3390/ph15020187. Pharmaceuticals (Basel). 2022. PMID: 35215299 Free PMC article. Review.

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