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Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC.
Abdelazeem KNM, Nguyen D, Corbo S, Darragh LB, Matsumoto MW, Van Court B, Neupert B, Yu J, Olimpo NA, Osborne DG, Gadwa J, Ross RB, Nguyen A, Bhatia S, Kapoor M, Friedman RS, Jacobelli J, Saviola AJ, Knitz MW, Pasquale EB, Karam SD. Abdelazeem KNM, et al. Among authors: osborne dg. Oncogene. 2024 Nov 3. doi: 10.1038/s41388-024-03208-9. Online ahead of print. Oncogene. 2024. PMID: 39489818
CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients.
Vaddi PK, Osborne DG, Nicklawsky A, Williams NK, Menon DR, Smith D, Mayer J, Reid A, Domenico J, Nguyen GH, Robinson WA, Ziman M, Gao D, Zhai Z, Fujita M. Vaddi PK, et al. Among authors: osborne dg. Front Immunol. 2023 May 1;14:1173035. doi: 10.3389/fimmu.2023.1173035. eCollection 2023. Front Immunol. 2023. PMID: 37197667 Free PMC article.
Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC.
Abdelazeem KNM, Nguyen D, Corbo S, Darragh LB, Matsumoto MW, Court BV, Neupert B, Yu J, Olimpo NA, Osborne DG, Gadwa J, Ross RB, Nguyen A, Bhatia S, Kapoor M, Friedman RS, Jacobelli J, Saviola AJ, Knitz MW, Pasquale EB, Karam SD. Abdelazeem KNM, et al. Among authors: osborne dg. bioRxiv [Preprint]. 2024 Jul 23:2024.07.21.604518. doi: 10.1101/2024.07.21.604518. bioRxiv. 2024. Update in: Oncogene. 2024 Nov 3. doi: 10.1038/s41388-024-03208-9 PMID: 39091728 Free PMC article. Updated. Preprint.
Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation.
Johnson JL, Meneses-Salas E, Ramadass M, Monfregola J, Rahman F, Carvalho Gontijo R, Kiosses WB, Pestonjamasp K, Allen D, Zhang J, Osborne DG, Zhu YP, Wineinger N, Askari K, Chen D, Yu J, Henderson SC, Hedrick CC, Ursini MV, Grinstein S, Billadeau DD, Catz SD. Johnson JL, et al. Among authors: osborne dg. Nat Commun. 2022 Sep 21;13(1):5529. doi: 10.1038/s41467-022-33230-y. Nat Commun. 2022. PMID: 36130971 Free PMC article.
Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.
Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Knitz MW, et al. Among authors: osborne dg. J Immunother Cancer. 2021 Apr;9(4):e001955. doi: 10.1136/jitc-2020-001955. J Immunother Cancer. 2021. PMID: 33883256 Free PMC article.
Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.
Tengesdal IW, Menon DR, Osborne DG, Neff CP, Powers NE, Gamboni F, Mauro AG, D'Alessandro A, Stefanoni D, Henen MA, Mills TS, De Graaf DM, Azam T, Vogeli B, Palmer BE, Pietras EM, DeGregori J, Tan AC, Joosten LAB, Fujita M, Dinarello CA, Marchetti C. Tengesdal IW, et al. Among authors: osborne dg. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2000915118. doi: 10.1073/pnas.2000915118. Proc Natl Acad Sci U S A. 2021. PMID: 33649199 Free PMC article.
35 results