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Page 1
Targeting PI3Kγ Pathway for Treating Dengue virus Infection.
da S Santos FR, Valadão DF, Bambirra JL, Moreira TP, de Souza CDF, Passos IBS, Queiroz-Junior CM, Fagundes CT, Teixeira MM, Costa VV, Souza DG. da S Santos FR, et al. Among authors: costa vv. Microb Pathog. 2024 Oct 25:107060. doi: 10.1016/j.micpath.2024.107060. Online ahead of print. Microb Pathog. 2024. PMID: 39490942
IFN-γ production depends on IL-12 and IL-18 combined action and mediates host resistance to dengue virus infection in a nitric oxide-dependent manner.
Fagundes CT, Costa VV, Cisalpino D, Amaral FA, Souza PR, Souza RS, Ryffel B, Vieira LQ, Silva TA, Atrasheuskaya A, Ignatyev G, Sousa LP, Souza DG, Teixeira MM. Fagundes CT, et al. Among authors: costa vv. PLoS Negl Trop Dis. 2011 Dec;5(12):e1449. doi: 10.1371/journal.pntd.0001449. Epub 2011 Dec 20. PLoS Negl Trop Dis. 2011. PMID: 22206036 Free PMC article.
Subversion of early innate antiviral responses during antibody-dependent enhancement of Dengue virus infection induces severe disease in immunocompetent mice.
Costa VV, Fagundes CT, Valadão DF, Ávila TV, Cisalpino D, Rocha RF, Ribeiro LS, Ascenção FR, Kangussu LM, Celso MQ Jr, Astigarraga RG, Gouveia FL, Silva TA, Bonaventura D, Sampaio Dde A, Leite AC, Teixeira MM, Souza DG. Costa VV, et al. Med Microbiol Immunol. 2014 Aug;203(4):231-50. doi: 10.1007/s00430-014-0334-5. Epub 2014 Apr 11. Med Microbiol Immunol. 2014. PMID: 24723052
Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide.
Jackman JA, Costa VV, Park S, Real ALCV, Park JH, Cardozo PL, Ferhan AR, Olmo IG, Moreira TP, Bambirra JL, Queiroz VF, Queiroz-Junior CM, Foureaux G, Souza DG, Ribeiro FM, Yoon BK, Wynendaele E, De Spiegeleer B, Teixeira MM, Cho NJ. Jackman JA, et al. Among authors: costa vv. Nat Mater. 2018 Nov;17(11):971-977. doi: 10.1038/s41563-018-0194-2. Epub 2018 Oct 22. Nat Mater. 2018. PMID: 30349030
A model of DENV-3 infection that recapitulates severe disease and highlights the importance of IFN-γ in host resistance to infection.
Costa VV, Fagundes CT, Valadão DF, Cisalpino D, Dias AC, Silveira KD, Kangussu LM, Ávila TV, Bonfim MR, Bonaventura D, Silva TA, Sousa LP, Rachid MA, Vieira LQ, Menezes GB, de Paula AM, Atrasheuskaya A, Ignatyev G, Teixeira MM, Souza DG. Costa VV, et al. PLoS Negl Trop Dis. 2012;6(5):e1663. doi: 10.1371/journal.pntd.0001663. Epub 2012 May 29. PLoS Negl Trop Dis. 2012. PMID: 22666512 Free PMC article.
Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses.
Zandi K, Bassit L, Amblard F, Cox BD, Hassandarvish P, Moghaddam E, Yueh A, Libanio Rodrigues GO, Passos I, Costa VV, AbuBakar S, Zhou L, Kohler J, Teixeira MM, Schinazi RF. Zandi K, et al. Among authors: costa vv. Antimicrob Agents Chemother. 2019 Jun 24;63(7):e00397-19. doi: 10.1128/AAC.00397-19. Print 2019 Jul. Antimicrob Agents Chemother. 2019. PMID: 31061163 Free PMC article.
In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy.
Camargos VN, Foureaux G, Medeiros DC, da Silveira VT, Queiroz-Junior CM, Matosinhos ALB, Figueiredo AFA, Sousa CDF, Moreira TP, Queiroz VF, Dias ACF, Santana KTO, Passos I, Real ALCV, Silva LC, Mourão FAG, Wnuk NT, Oliveira MAP, Macari S, Silva T, Garlet GP, Jackman JA, Soriani FM, Moraes MFD, Mendes EMAM, Ribeiro FM, Costa GMJ, Teixeira AL, Cho NJ, Oliveira ACP, Teixeira MM, Costa VV, Souza DG. Camargos VN, et al. Among authors: costa gmj, costa vv. EBioMedicine. 2019 Jun;44:516-529. doi: 10.1016/j.ebiom.2019.05.014. Epub 2019 May 23. EBioMedicine. 2019. PMID: 31130472 Free PMC article.
Phosphoinositide-3 kinase gamma regulates caspase-1 activation and leukocyte recruitment in acute murine gout.
Tavares LD, Galvão I, Costa VV, Batista NV, Rossi LCR, Brito CB, Reis AC, Queiroz-Junior CM, Braga AD, Coelho FM, Dias AC, Zamboni DS, Pinho V, Teixeira MM, Amaral FA, Souza DG. Tavares LD, et al. Among authors: costa vv. J Leukoc Biol. 2019 Sep;106(3):619-629. doi: 10.1002/JLB.MA1118-470RR. Epub 2019 Aug 8. J Leukoc Biol. 2019. PMID: 31392775
Acute coronavirus infection triggers a TNF-dependent osteoporotic phenotype in mice.
Queiroz-Junior CM, Santos ACPM, Gonçalves MR, Brito CB, Barrioni B, Almeida PJ, Gonçalves-Pereira MH, Silva T, Oliveira SR, Pereira MM, Santiago HC, Teixeira MM, Costa VV. Queiroz-Junior CM, et al. Among authors: costa vv. Life Sci. 2023 Jul 1;324:121750. doi: 10.1016/j.lfs.2023.121750. Epub 2023 May 2. Life Sci. 2023. PMID: 37142087 Free PMC article.
104 results