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Page 1
AAVolve: Concatenated long-read deep sequencing enables whole capsid tracking during shuffled AAV library selection.
Scott S, Westhaus A, Nazareth D, Cabanes-Creus M, Navarro RG, Chandra D, Zhu E, Venkateswaran A, Alexander IE, Bauer DC, Wilson LOW, Lisowski L. Scott S, et al. Among authors: westhaus a. Mol Ther Methods Clin Dev. 2024 Oct 4;32(4):101351. doi: 10.1016/j.omtm.2024.101351. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39498467 Free PMC article.
Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations.
Drouyer M, Merjane J, Nedelkoska T, Westhaus A, Scott S, Lee S, Burke PGR, McMullan S, Lanciego JL, Vicente AF, Bugallo R, Unzu C, González-Aseguinolaza G, Gonzalez-Cordero A, Lisowski L. Drouyer M, et al. Among authors: westhaus a. Mol Ther Nucleic Acids. 2024 Jun 28;35(3):102264. doi: 10.1016/j.omtn.2024.102264. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39108635 Free PMC article.
Novel AAV variants with improved tropism for human Schwann cells.
Drouyer M, Chu TH, Labit E, Haase F, Navarro RG, Nazareth D, Rosin N, Merjane J, Scott S, Cabanes-Creus M, Westhaus A, Zhu E, Midha R, Alexander IE, Biernaskie J, Ginn SL, Lisowski L. Drouyer M, et al. Among authors: westhaus a. Mol Ther Methods Clin Dev. 2024 Mar 11;32(2):101234. doi: 10.1016/j.omtm.2024.101234. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38558569 Free PMC article.
Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation.
Cabanes-Creus M, Liao SHY, Gale Navarro R, Knight M, Nazareth D, Lau NS, Ly M, Zhu E, Roca-Pinilla R, Bugallo Delgado R, Vicente AF, Baltazar G, Westhaus A, Merjane J, Crawford M, McCaughan GW, Unzu C, González-Aseguinolaza G, Alexander IE, Pulitano C, Lisowski L. Cabanes-Creus M, et al. Among authors: westhaus a. Nat Commun. 2024 Mar 14;15(1):1876. doi: 10.1038/s41467-024-46194-y. Nat Commun. 2024. PMID: 38485924 Free PMC article.
AAV capsid bioengineering in primary human retina models.
Westhaus A, Eamegdool SS, Fernando M, Fuller-Carter P, Brunet AA, Miller AL, Rashwan R, Knight M, Daniszewski M, Lidgerwood GE, Pébay A, Hewitt A, Santilli G, Thrasher AJ, Carvalho LS, Gonzalez-Cordero A, Jamieson RV, Lisowski L. Westhaus A, et al. Sci Rep. 2023 Dec 11;13(1):21946. doi: 10.1038/s41598-023-49112-2. Sci Rep. 2023. PMID: 38081924 Free PMC article.
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors.
Westhaus A, Cabanes-Creus M, Dilworth KL, Zhu E, Salas Gómez D, Navarro RG, Amaya AK, Scott S, Kwiatek M, McCorkindale AL, Hayman TE, Frahm S, Perocheau DP, Tran BM, Vincan E, Wong SL, Waters SA, Riddiough GE, Perini MV, Wilson LOW, Baruteau J, Diecke S, González-Aseguinolaza G, Santilli G, Thrasher AJ, Alexander IE, Lisowski L. Westhaus A, et al. Hum Gene Ther. 2023 Apr;34(7-8):273-288. doi: 10.1089/hum.2022.188. Hum Gene Ther. 2023. PMID: 36927149 Free PMC article.
AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression.
Westhaus A, Cabanes-Creus M, Jonker T, Sallard E, Navarro RG, Zhu E, Baltazar Torres G, Lee S, Wilmott P, Gonzalez-Cordero A, Santilli G, Thrasher AJ, Alexander IE, Lisowski L. Westhaus A, et al. Hum Gene Ther. 2022 Jun;33(11-12):664-682. doi: 10.1089/hum.2021.278. Epub 2022 May 6. Hum Gene Ther. 2022. PMID: 35297686 Free PMC article.
17 results