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Markov field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.
Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Wang S, et al. Among authors: irvine eb. Cell Syst. 2024 Oct 29:S2405-4712(24)00298-9. doi: 10.1016/j.cels.2024.10.001. Online ahead of print. Cell Syst. 2024. PMID: 39504969 Free article.
Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques.
Irvine EB, O'Neil A, Darrah PA, Shin S, Choudhary A, Li W, Honnen W, Mehra S, Kaushal D, Gideon HP, Flynn JL, Roederer M, Seder RA, Pinter A, Fortune S, Alter G. Irvine EB, et al. Nat Immunol. 2021 Dec;22(12):1515-1523. doi: 10.1038/s41590-021-01066-1. Epub 2021 Nov 22. Nat Immunol. 2021. PMID: 34811542 Free PMC article.
Airway T cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques.
Darrah PA, Zeppa JJ, Wang C, Irvine EB, Bucsan AN, Rodgers MA, Pokkali S, Hackney JA, Kamath M, White AG, Borish HJ, Frye LJ, Tomko J, Kracinovsky K, Lin PL, Klein E, Scanga CA, Alter G, Fortune SM, Lauffenburger DA, Flynn JL, Seder RA, Maiello P, Roederer M. Darrah PA, et al. Among authors: irvine eb. Cell Host Microbe. 2023 Jun 14;31(6):962-977.e8. doi: 10.1016/j.chom.2023.05.006. Epub 2023 Jun 1. Cell Host Microbe. 2023. PMID: 37267955 Free PMC article.
Protective intravenous BCG vaccination induces enhanced immune signaling in the airways.
Peters JM, Irvine EB, Rosenberg JM, Wadsworth MH, Hughes TK, Sutton M, Nyquist SK, Bromley JD, Mondal R, Roederer M, Seder RA, Darrah PA, Alter G, Flynn JL, Shalek AK, Fortune SM, Bryson BD. Peters JM, et al. Among authors: irvine eb. bioRxiv [Preprint]. 2023 Jul 18:2023.07.16.549208. doi: 10.1101/2023.07.16.549208. bioRxiv. 2023. PMID: 37502895 Free PMC article. Preprint.
Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis.
Irvine EB, Nikolov A, Khan MZ, Peters JM, Lu R, Sixsmith J, Wallace A, van Woudenbergh E, Shin S, Karpinski W, Hsiao JC, Casadevall A, Bryson BD, Cavacini L, Grace PS, Alter G, Fortune SM. Irvine EB, et al. Nat Microbiol. 2024 Sep;9(9):2369-2382. doi: 10.1038/s41564-024-01777-9. Epub 2024 Aug 22. Nat Microbiol. 2024. PMID: 39174703 Free PMC article.
18 results