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Automated Continuous Evolution of Proteins in Vivo.
Zhong Z, Wong BG, Ravikumar A, Arzumanyan GA, Khalil AS, Liu CC. Zhong Z, et al. Among authors: liu cc. ACS Synth Biol. 2020 Jun 19;9(6):1270-1276. doi: 10.1021/acssynbio.0c00135. Epub 2020 May 12. ACS Synth Biol. 2020. PMID: 32374988 Free PMC article.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Among authors: liu cc. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.
An in silico method to assess antibody fragment polyreactivity.
Harvey EP, Shin JE, Skiba MA, Nemeth GR, Hurley JD, Wellner A, Shaw AY, Miranda VG, Min JK, Liu CC, Marks DS, Kruse AC. Harvey EP, et al. Among authors: liu cc. Nat Commun. 2022 Dec 7;13(1):7554. doi: 10.1038/s41467-022-35276-4. Nat Commun. 2022. PMID: 36477674 Free PMC article.
In vivo hypermutation and continuous evolution.
Molina RS, Rix G, Mengiste AA, Alvarez B, Seo D, Chen H, Hurtado J, Zhang Q, Donato García-García J, Heins ZJ, Almhjell PJ, Arnold FH, Khalil AS, Hanson AD, Dueber JE, Schaffer DV, Chen F, Kim S, Ángel Fernández L, Shoulders MD, Liu CC. Molina RS, et al. Among authors: liu cc. Nat Rev Methods Primers. 2022;2:37. doi: 10.1038/s43586-022-00130-w. Epub 2022 May 19. Nat Rev Methods Primers. 2022. PMID: 37073402 Free PMC article. No abstract available.
2,797 results