Hahn G - Search Results

1

Assessing polyomic risk to predict Alzheimer's disease using a machine learning model.

Ngai T, Willett J, Waqas M, Fishbein LH, Choi Y, Hahn G, Mullin K, Lange C, Hecker J, Tanzi RE, Prokopenko D. Ngai T, et al. Among authors: hahn g. Alzheimers Dement. 2024 Nov 7. doi: 10.1002/alz.14319. Online ahead of print. Alzheimers Dement. 2024. PMID: 39511865

2

On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.

Lee S, Hecker J, Hahn G, Mullin K; Alzheimer's Disease Neuroimaging Initiative (ADNI); Lutz SM, Tanzi RE, Lange C, Prokopenko D. Lee S, et al. Among authors: hahn g. Alzheimers Dement. 2024 May;20(5):3397-3405. doi: 10.1002/alz.13796. Epub 2024 Apr 2. Alzheimers Dement. 2024. PMID: 38563508 Free PMC article.

3

A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.

Hahn G, Prokopenko D, Lutz SM, Mullin K, Tanzi RE, Cho MH, Silverman EK, Lange C, On The Behalf Of The Nhlbi Trans-Omics For Precision Medicine TOPMed Consortium. Hahn G, et al. Genes (Basel). 2022 Jan 6;13(1):112. doi: 10.3390/genes13010112. Genes (Basel). 2022. PMID: 35052450 Free PMC article.

4

Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data.

Hahn G, Prokopenko D, Hecker J, Lutz SM, Mullin K, Sejour L, Hide W, Vlachos I, DeSantis S, Tanzi RE, Lange C. Hahn G, et al. Brief Bioinform. 2024 May 23;25(4):bbae267. doi: 10.1093/bib/bbae267. Brief Bioinform. 2024. PMID: 38836403 Free PMC article.

5

Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model.

Hahn G, Prokopenko D, Hecker J, Lutz SM, Mullin K, Tanzi RE, DeSantis S, Lange C. Hahn G, et al. Genet Epidemiol. 2024 Jul 9. doi: 10.1002/gepi.22581. Online ahead of print. Genet Epidemiol. 2024. PMID: 38982682

6

A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.

Lee S, Hahn G, Hecker J, Lutz SM, Mullin K; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Hide W, Bertram L, DeMeo DL, Tanzi RE, Lange C, Prokopenko D. Lee S, et al. Among authors: hahn g. Brief Bioinform. 2023 Jan 19;24(1):bbac611. doi: 10.1093/bib/bbac611. Brief Bioinform. 2023. PMID: 36585781 Free PMC article.

7

Fast computation of the eigensystem of genomic similarity matrices.

Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C. Hahn G, et al. BMC Bioinformatics. 2024 Jan 25;25(1):43. doi: 10.1186/s12859-024-05650-8. BMC Bioinformatics. 2024. PMID: 38273228 Free PMC article.

8

Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex.

Voorhies K, Hecker J, Lee S, Hahn G, Prokopenko D, McDonald ML, Wu AC, Wu A, Hokanson JE, Cho MH, Lange C, Hoth KF, Lutz SM. Voorhies K, et al. Among authors: hahn g. Genes (Basel). 2024 Apr 27;15(5):565. doi: 10.3390/genes15050565. Genes (Basel). 2024. PMID: 38790194 Free PMC article.

9

locStra: Fast analysis of regional/global stratification in whole-genome sequencing studies.

Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Hahn G, et al. Genet Epidemiol. 2021 Feb;45(1):82-98. doi: 10.1002/gepi.22356. Epub 2020 Sep 14. Genet Epidemiol. 2021. PMID: 32929743 Free PMC article.

10

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.

Hahn G, Lee S, Prokopenko D, Abraham J, Novak T, Hecker J, Cho M, Khurana S, Baden LR, Randolph AG, Weiss ST, Lange C. Hahn G, et al. BMC Bioinformatics. 2022 Dec 19;23(1):547. doi: 10.1186/s12859-022-05105-y. BMC Bioinformatics. 2022. PMID: 36536276 Free PMC article.

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