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Aromatic Amino Acid Hydroxylases as Off-Targets of Histone Deacetylase Inhibitors.
Baumann A, Papenkordt N, Robaa D, Szigetvari PD, Vogelmann A, Bracher F, Sippl W, Jung M, Haavik J. Baumann A, et al. Among authors: sippl w. ACS Chem Neurosci. 2024 Nov 20;15(22):4143-4155. doi: 10.1021/acschemneuro.4c00346. Epub 2024 Nov 10. ACS Chem Neurosci. 2024. PMID: 39523540 Free PMC article.
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
Vögerl K, Ong N, Senger J, Herp D, Schmidtkunz K, Marek M, Müller M, Bartel K, Shaik TB, Porter NJ, Robaa D, Christianson DW, Romier C, Sippl W, Jung M, Bracher F. Vögerl K, et al. Among authors: sippl w. J Med Chem. 2019 Feb 14;62(3):1138-1166. doi: 10.1021/acs.jmedchem.8b01090. Epub 2019 Feb 1. J Med Chem. 2019. PMID: 30645113 Free PMC article.
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases.
Roatsch M, Hoffmann I, Abboud MI, Hancock RL, Tarhonskaya H, Hsu KF, Wilkins SE, Yeh TL, Lippl K, Serrer K, Moneke I, Ahrens TD, Robaa D, Wenzler S, Barthes NPF, Franz H, Sippl W, Lassmann S, Diederichs S, Schleicher E, Schofield CJ, Kawamura A, Schüle R, Jung M. Roatsch M, et al. Among authors: sippl w. ACS Chem Biol. 2019 Aug 16;14(8):1737-1750. doi: 10.1021/acschembio.9b00289. Epub 2019 Jul 19. ACS Chem Biol. 2019. PMID: 31287655
Proteolysis targeting chimeras (PROTACs) for epigenetics research.
Vogelmann A, Robaa D, Sippl W, Jung M. Vogelmann A, et al. Among authors: sippl w. Curr Opin Chem Biol. 2020 Aug;57:8-16. doi: 10.1016/j.cbpa.2020.01.010. Epub 2020 Mar 5. Curr Opin Chem Biol. 2020. PMID: 32146413 Free article. Review.
Strategies To Design Selective Histone Deacetylase Inhibitors.
Melesina J, Simoben CV, Praetorius L, Bülbül EF, Robaa D, Sippl W. Melesina J, et al. Among authors: sippl w. ChemMedChem. 2021 May 6;16(9):1336-1359. doi: 10.1002/cmdc.202000934. Epub 2021 Feb 19. ChemMedChem. 2021. PMID: 33428327 Review.
Histone deacetylase inhibitors that target tubulin.
Schemies J, Sippl W, Jung M. Schemies J, et al. Among authors: sippl w. Cancer Lett. 2009 Aug 8;280(2):222-32. doi: 10.1016/j.canlet.2009.01.040. Epub 2009 Mar 5. Cancer Lett. 2009. PMID: 19268440 Review.
290 results