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High glycemic variability is associated with a reduced T cell cytokine response to influenza A virus.
Tong MZW, Hulme KD, Law SC, Noye E, Dorey ES, Chew KY, Rowntree LC, van de Sandt CE, Kedzierska K, Goeijenbier M, Ronacher K, Alzaid F, Julla JB, Riveline JP, Lineburg KE, Smith C, Grant EJ, Gras S, Gallo LA, Barrett HL, Short KR. Tong MZW, et al. Among authors: gras s. iScience. 2024 Oct 11;27(11):111166. doi: 10.1016/j.isci.2024.111166. eCollection 2024 Nov 15. iScience. 2024. PMID: 39524368 Free PMC article.
Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus.
Hulme KD, Tong ZWM, Rowntree LC, van de Sandt CE, Ronacher K, Grant EJ, Dorey ES, Gallo LA, Gras S, Kedzierska K, Barrett HL, Short KR. Hulme KD, et al. Among authors: gras s. Cell Mol Life Sci. 2024 Jan 12;81(1):35. doi: 10.1007/s00018-023-05010-4. Cell Mol Life Sci. 2024. PMID: 38214784 Free PMC article.
The presentation of SARS-CoV-2 peptides by the common HLA-A∗02:01 molecule.
Szeto C, Chatzileontiadou DSM, Nguyen AT, Sloane H, Lobos CA, Jayasinghe D, Halim H, Smith C, Riboldi-Tunnicliffe A, Grant EJ, Gras S. Szeto C, et al. Among authors: gras s. iScience. 2021 Feb 19;24(2):102096. doi: 10.1016/j.isci.2021.102096. Epub 2021 Jan 22. iScience. 2021. PMID: 33521593 Free PMC article.
Elevated BMI reduces the humoral response to SARS-CoV-2 infection.
Tong MZ, Sng JD, Carney M, Cooper L, Brown S, Lineburg KE, Chew KY, Collins N, Ignacio K, Airey M, Burr L, Joyce BA, Jayasinghe D, McMillan CL, Muller DA, Adhikari A, Gallo LA, Dorey ES, Barrett HL, Gras S, Smith C, Good-Jacobson K, Short KR. Tong MZ, et al. Among authors: gras s. Clin Transl Immunology. 2023 Dec 3;12(12):e1476. doi: 10.1002/cti2.1476. eCollection 2023. Clin Transl Immunology. 2023. PMID: 38050635 Free PMC article.
Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph.
van de Sandt CE, Clemens EB, Grant EJ, Rowntree LC, Sant S, Halim H, Crowe J, Cheng AC, Kotsimbos TC, Richards M, Miller A, Tong SYC, Rossjohn J, Nguyen THO, Gras S, Chen W, Kedzierska K. van de Sandt CE, et al. Among authors: gras s. Nat Commun. 2019 Dec 6;10(1):5579. doi: 10.1038/s41467-019-13346-4. Nat Commun. 2019. PMID: 31811120 Free PMC article.
HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.
Sant S, Quiñones-Parra SM, Koutsakos M, Grant EJ, Loudovaris T, Mannering SI, Crowe J, van de Sandt CE, Rimmelzwaan GF, Rossjohn J, Gras S, Loh L, Nguyen THO, Kedzierska K. Sant S, et al. Among authors: gras s. PLoS Pathog. 2020 Aug 4;16(8):e1008714. doi: 10.1371/journal.ppat.1008714. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32750095 Free PMC article.
CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
Lineburg KE, Grant EJ, Swaminathan S, Chatzileontiadou DSM, Szeto C, Sloane H, Panikkar A, Raju J, Crooks P, Rehan S, Nguyen AT, Lekieffre L, Neller MA, Tong ZWM, Jayasinghe D, Chew KY, Lobos CA, Halim H, Burrows JM, Riboldi-Tunnicliffe A, Chen W, D'Orsogna L, Khanna R, Short KR, Smith C, Gras S. Lineburg KE, et al. Among authors: gras s. Immunity. 2021 May 11;54(5):1055-1065.e5. doi: 10.1016/j.immuni.2021.04.006. Epub 2021 Apr 13. Immunity. 2021. PMID: 33945786 Free PMC article.
389 results