Hu Q - Search Results

1

Macrophage P2Y₆R activation aggravates psoriatic inflammation through IL-27-mediated Th1 responses.

Yin L, Zhang E, Mao T, Zhu Y, Ni S, Li Y, Liu C, Fang Y, Ni K, Lu Y, Li H, Zhou M, Hu Q. Yin L, et al. Among authors: hu q. Acta Pharm Sin B. 2024 Oct;14(10):4360-4377. doi: 10.1016/j.apsb.2024.06.008. Epub 2024 Jun 20. Acta Pharm Sin B. 2024. PMID: 39525587 Free PMC article.

2

The role of P2Y₆R in cardiovascular diseases and recent development of P2Y₆R antagonists.

Zhou M, Wang W, Li Y, Zhang Q, Ji H, Li H, Hu Q. Zhou M, et al. Among authors: hu q. Drug Discov Today. 2020 Mar;25(3):568-573. doi: 10.1016/j.drudis.2019.12.015. Epub 2020 Jan 8. Drug Discov Today. 2020. PMID: 31926135 Review.

3

Discovery of Selective P2Y₆R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy.

Zhu Y, Zhou M, Cheng X, Wang H, Li Y, Guo Y, Wang Y, Tian S, Mao T, Zhang Z, Li D, Hu Q, Li H. Zhu Y, et al. Among authors: hu q. J Med Chem. 2023 May 11;66(9):6315-6332. doi: 10.1021/acs.jmedchem.3c00210. Epub 2023 Apr 20. J Med Chem. 2023. PMID: 37078976

4

Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cβ/store-operated calcium entry/calreticulin/scavenger receptor A pathways.

Li Y, Zhou M, Li H, Dai C, Yin L, Liu C, Li Y, Zhang E, Dong X, Ji H, Hu Q. Li Y, et al. Among authors: hu q. Eur Heart J. 2024 Jan 27;45(4):268-283. doi: 10.1093/eurheartj/ehad796. Eur Heart J. 2024. PMID: 38036416

5

Targeting P2Y₁₄R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis.

Liu C, Wang H, Han L, Zhu Y, Ni S, Zhi J, Yang X, Zhi J, Sheng T, Li H, Hu Q. Liu C, et al. Among authors: hu q. Nat Commun. 2024 Mar 7;15(1):2083. doi: 10.1038/s41467-024-46365-x. Nat Commun. 2024. PMID: 38453952 Free PMC article.

6

Comprehensive insights into potential roles of purinergic P2 receptors on diseases: Signaling pathways involved and potential therapeutics.

Guo Y, Mao T, Fang Y, Wang H, Yu J, Zhu Y, Shen S, Zhou M, Li H, Hu Q. Guo Y, et al. Among authors: hu q. J Adv Res. 2024 Mar 31:S2090-1232(24)00123-1. doi: 10.1016/j.jare.2024.03.027. Online ahead of print. J Adv Res. 2024. PMID: 38565403 Free article. Review.

7

HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.

Yang X, Ji J, Liu C, Zhou M, Li H, Ye S, Hu Q. Yang X, et al. Among authors: hu q. Int Immunopharmacol. 2020 Jun;83:106383. doi: 10.1016/j.intimp.2020.106383. Epub 2020 Mar 16. Int Immunopharmacol. 2020. PMID: 32193099

8

GPR105-Targeted Therapy Promotes Gout Resolution as a Switch Between NETosis and Apoptosis of Neutrophils.

Liu C, Zhou M, Jiang W, Ye S, Tian S, Jiang C, Hao K, Li H, Hu Q. Liu C, et al. Among authors: hu q. Front Immunol. 2022 Mar 30;13:870183. doi: 10.3389/fimmu.2022.870183. eCollection 2022. Front Immunol. 2022. PMID: 35432308 Free PMC article.

9

Neutrophil CC1 plays a protective role in orthotopic liver transplantation: views from the perspective of natural compounds.

Fang Y, Hu Q. Fang Y, et al. Among authors: hu q. Chin J Nat Med. 2023 Apr;21(4):241-242. doi: 10.1016/S1875-5364(23)60432-7. Chin J Nat Med. 2023. PMID: 37120242 No abstract available.

10

Structure-based virtual screening for discovery of paederosidic acid from Paederia scandens as novel P2Y₁₄R antagonist.

Li Y, Li Y, Zhu Y, Ji W, Wang Y, Dong X, Zhao X, Wang T, Tian S, Hu Q, Li H, Zhou M. Li Y, et al. Among authors: hu q. Phytomedicine. 2023 Jul;115:154851. doi: 10.1016/j.phymed.2023.154851. Epub 2023 May 2. Phytomedicine. 2023. PMID: 37149963

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