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Page 1
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation.
Bertran MT, Walmsley R, Cummings T, Aramburu IV, Benton DJ, Mora Molina R, Assalaarachchi J, Chasampalioti M, Swanton T, Joshi D, Federico S, Okkenhaug H, Yu L, Oxley D, Walker S, Papayannopoulos V, Suga H, Christophorou MA, Walport LJ. Bertran MT, et al. Among authors: aramburu iv. Nat Commun. 2024 Nov 11;15(1):9746. doi: 10.1038/s41467-024-53554-1. Nat Commun. 2024. PMID: 39528459 Free PMC article.
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils.
Huerga Encabo H, Aramburu IV, Garcia-Albornoz M, Piganeau M, Wood H, Song A, Ferrelli A, Sharma A, Minutti CM, Domart MC, Papazoglou D, Gurashi K, Llorian Sopena M, Goldstone R, Fallesen T, Wang Q, Ariza-McNaughton L, Wiseman DH, Batta K, Gupta R, Papayannopoulos V, Bonnet D. Huerga Encabo H, et al. Among authors: aramburu iv. Cell Stem Cell. 2023 Jun 1;30(6):781-799.e9. doi: 10.1016/j.stem.2023.05.004. Cell Stem Cell. 2023. PMID: 37267914 Free article.
Functional proteomic profiling links deficient DNA clearance with increased mortality in individuals with severe COVID-19 pneumonia.
Aramburu IV, Hoving D, Vernardis SI, Tin MCF, Ioannou M, Temkin MI, De Vasconcelos NM, Demichev V, Helbig ET, Lippert L, Stahl K, White M, Radbruch H, Ihlow J, Horst D, Chiesa ST, Deanfield JE, David S, Bode C, Kurth F, Ralser M, Papayannopoulos V. Aramburu IV, et al. Immunity. 2022 Dec 13;55(12):2436-2453.e5. doi: 10.1016/j.immuni.2022.11.007. Epub 2022 Nov 17. Immunity. 2022. PMID: 36462503 Free PMC article.
Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
Porter JC, Inshaw J, Solis VJ, Denneny E, Evans R, Temkin MI, De Vasconcelos N, Aramburu IV, Hoving D, Basire D, Crissell T, Guinto J, Webb A, Esmail H, Johnston V, Last A, Rampling T, Lippert L, Helbig ET, Kurth F, Williams B, Flynn A, Lukey PT, Birault V, Papayannopoulos V. Porter JC, et al. Among authors: aramburu iv. Elife. 2024 Jul 16;12:RP87030. doi: 10.7554/eLife.87030. Elife. 2024. PMID: 39009040 Free PMC article. Clinical Trial.
Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening.
Ioannou M, Hoving D, Aramburu IV, Temkin MI, De Vasconcelos NM, Tsourouktsoglou TD, Wang Q, Boeing S, Goldstone R, Vernardis S, Demichev V, Ralser M, David S, Stahl K, Bode C, Papayannopoulos V. Ioannou M, et al. Among authors: aramburu iv. Nat Commun. 2022 Aug 9;13(1):4658. doi: 10.1038/s41467-022-32320-1. Nat Commun. 2022. PMID: 35945238 Free PMC article.
Neutrophil extracellular traps: from physiology to pathology.
Hidalgo A, Libby P, Soehnlein O, Aramburu IV, Papayannopoulos V, Silvestre-Roig C. Hidalgo A, et al. Among authors: aramburu iv. Cardiovasc Res. 2022 Oct 21;118(13):2737-2753. doi: 10.1093/cvr/cvab329. Cardiovasc Res. 2022. PMID: 34648022 Free PMC article. Review.
Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients.
Huerga Encabo H, Grey W, Garcia-Albornoz M, Wood H, Ulferts R, Aramburu IV, Kulasekararaj AG, Mufti G, Papayannopoulos V, Beale R, Bonnet D. Huerga Encabo H, et al. Among authors: aramburu iv. Stem Cell Reports. 2021 Mar 9;16(3):428-436. doi: 10.1016/j.stemcr.2021.02.001. Epub 2021 Feb 5. Stem Cell Reports. 2021. PMID: 33581053 Free PMC article.
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis.
Moreira-Teixeira L, Stimpson PJ, Stavropoulos E, Hadebe S, Chakravarty P, Ioannou M, Aramburu IV, Herbert E, Priestnall SL, Suarez-Bonnet A, Sousa J, Fonseca KL, Wang Q, Vashakidze S, Rodríguez-Martínez P, Vilaplana C, Saraiva M, Papayannopoulos V, O'Garra A. Moreira-Teixeira L, et al. Among authors: aramburu iv. Nat Commun. 2020 Nov 4;11(1):5566. doi: 10.1038/s41467-020-19412-6. Nat Commun. 2020. PMID: 33149141 Free PMC article.
17 results