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Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation.
Tu HJ, Chao MW, Lee CC, Peng CS, Wu YW, Lin TE, Chang YW, Yen SC, Hsu KC, Pan SL, HuangFu WC. Tu HJ, et al. Among authors: hsu kc. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2418470. doi: 10.1080/14756366.2024.2418470. Epub 2024 Nov 4. J Enzyme Inhib Med Chem. 2024. PMID: 39494990 Free PMC article.
Identification, biological evaluation, and crystallographic analysis of coumestrol as a novel dual-specificity tyrosine-phosphorylation-regulated kinase 1A inhibitor.
Peng CH, Hwang TL, Hung SC, Tu HJ, Tseng YT, Lin TE, Lee CC, Tseng YC, Ko CY, Yen SC, Hsu KC, Pan SL, HuangFu WC. Peng CH, et al. Among authors: hsu kc. Int J Biol Macromol. 2024 Oct 29;282(Pt 4):136860. doi: 10.1016/j.ijbiomac.2024.136860. Online ahead of print. Int J Biol Macromol. 2024. PMID: 39481728 Free article.
552 results