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Page 1
Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.
Chen J, Zhang H, Fu T, Zhao J, Nowak JK, Kalla R, Wellens J, Yuan S, Noble A, Ventham NT, Dunlop MG, Halfvarson J, Mao R, Theodoratou E, Satsangi J, Li X. Chen J, et al. Among authors: dunlop mg. EBioMedicine. 2024 Nov 12;110:105443. doi: 10.1016/j.ebiom.2024.105443. Online ahead of print. EBioMedicine. 2024. PMID: 39536393 Free PMC article.
Exploring the cross-cancer effect of smoking and its fingerprints in blood DNA methylation on multiple cancers: A Mendelian randomization study.
Zhou Y, Zhou X, Sun J, Wang L, Zhao J, Chen J, Yuan S, He Y, Timofeeva M, Spiliopoulou A, Mesa-Eguiagaray I, Farrington SM, Ding K, Dunlop MG, Qian X, Theodoratou E, Li X. Zhou Y, et al. Among authors: dunlop mg. Int J Cancer. 2023 Oct 15;153(8):1477-1486. doi: 10.1002/ijc.34656. Epub 2023 Jul 14. Int J Cancer. 2023. PMID: 37449541 Free PMC article.
Genome-Wide Methylation Profiling in 229 Patients With Crohn's Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn's Disease (TOPPIC).
Ventham NT, Kennedy NA, Kalla R, Adams AT, Noble A, Ennis H; TOPPIC Study Group; IBD-BIOM Consortium; Mowat C, Dunlop MG, Satsangi J. Ventham NT, et al. Among authors: dunlop mg. Cell Mol Gastroenterol Hepatol. 2023;16(3):431-450. doi: 10.1016/j.jcmgh.2023.06.001. Epub 2023 Jun 17. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37331566 Free PMC article. Clinical Trial.
Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.
Rajasekaran V, Harris BT, Osborn RT, Smillie C, Donnelly K, Bacou M, Esiri-Bloom E, Ooi LY, Allan M, Walker M, Reid S, Meynert A, Grimes G, Blackmur JP, Vaughan-Shaw PG, Law PJ, Fernández-Rozadilla C, Tomlinson I, Houlston RS, Myant KB, Din FV, Timofeeva M, Dunlop MG, Farrington SM. Rajasekaran V, et al. Among authors: dunlop mg. Gut. 2024 Nov 28:gutjnl-2024-332121. doi: 10.1136/gutjnl-2024-332121. Online ahead of print. Gut. 2024. PMID: 39609081 Free article.
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes.
Chen Z, Guo X, Tao R, Huyghe JR, Law PJ, Fernandez-Rozadilla C, Ping J, Jia G, Long J, Li C, Shen Q, Xie Y, Timofeeva MN, Thomas M, Schmit SL, Díez-Obrero V, Devall M, Moratalla-Navarro F, Fernandez-Tajes J, Palles C, Sherwood K, Briggs SEW, Svinti V, Donnelly K, Farrington SM, Blackmur J, Vaughan-Shaw PG, Shu XO, Lu Y, Broderick P, Studd J, Harrison TA, Conti DV, Schumacher FR, Melas M, Rennert G, Obón-Santacana M, Martín-Sánchez V, Oh JH, Kim J, Jee SH, Jung KJ, Kweon SS, Shin MH, Shin A, Ahn YO, Kim DH, Oze I, Wen W, Matsuo K, Matsuda K, Tanikawa C, Ren Z, Gao YT, Jia WH, Hopper JL, Jenkins MA, Win AK, Pai RK, Figueiredo JC, Haile RW, Gallinger S, Woods MO, Newcomb PA, Duggan D, Cheadle JP, Kaplan R, Kerr R, Kerr D, Kirac I, Böhm J, Mecklin JP, Jousilahti P, Knekt P, Aaltonen LA, Rissanen H, Pukkala E, Eriksson JG, Cajuso T, Hänninen U, Kondelin J, Palin K, Tanskanen T, Renkonen-Sinisalo L, Männistö S, Albanes D, Weinstein SJ, Ruiz-Narvaez E, Palmer JR, Buchanan DD, Platz EA, Visvanathan K, Ulrich CM, Siegel E, Brezina S, Gsur A, Campbell PT, Chang-Claude J, Hoffmeister M, Brenner H, Slattery ML, Potter JD, Tsilidis KK, Schulze MB, Gunter MJ, Murphy N, Castells A, Castellví-Bel… See abstract for full author list ➔ Chen Z, et al. Among authors: dunlop mg. Nat Commun. 2024 Apr 26;15(1):3557. doi: 10.1038/s41467-024-47399-x. Nat Commun. 2024. PMID: 38670944 Free PMC article.
Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer.
Sun J, Zhao J, Zhou S, Li X, Li T, Wang L, Yuan S, Chen D, Law PJ, Larsson SC, Farrington SM, Houlston RS, Dunlop MG, Theodoratou E, Li X. Sun J, et al. Among authors: dunlop mg. J Natl Cancer Inst. 2024 Aug 1;116(8):1303-1312. doi: 10.1093/jnci/djae089. J Natl Cancer Inst. 2024. PMID: 38648753 Free PMC article.
262 results