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Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients.
Zhang X, Goedegebuure SP, Chen MY, Mishra R, Zhang F, Yu YY, Singhal K, Li L, Gao F, Myers NB, Vickery T, Hundal J, McLellan MD, Sturmoski MA, Kim SW, Chen I, Davidson JT 4th, Sankpal NV, Myles S, Suresh R, Ma CX, Foluso A, Wang-Gillam A, Davies S, Hagemann IS, Mardis ER, Griffith O, Griffith M, Miller CA, Hansen TH, Fleming TP, Schreiber RD, Gillanders WE. Zhang X, et al. Among authors: miller ca. Genome Med. 2024 Nov 14;16(1):131. doi: 10.1186/s13073-024-01388-3. Genome Med. 2024. PMID: 39538331 Free PMC article. Clinical Trial.
Breast Cancer Neoantigens Can Induce CD8+ T-Cell Responses and Antitumor Immunity.
Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, Miller CA, Ellis MJ, Mardis ER, Hansen T, Fleming TP, Goedegebuure SP, Gillanders WE. Zhang X, et al. Among authors: miller ca. Cancer Immunol Res. 2017 Jul;5(7):516-523. doi: 10.1158/2326-6066.CIR-16-0264. Epub 2017 Jun 15. Cancer Immunol Res. 2017. PMID: 28619968 Free PMC article.
Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.
Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE. Li L, et al. Among authors: miller ca. Genome Med. 2021 Apr 21;13(1):56. doi: 10.1186/s13073-021-00872-4. Genome Med. 2021. PMID: 33879241 Free PMC article.
Endogenous Neoantigen-Specific CD8 T Cells Identified in Two Glioblastoma Models Using a Cancer Immunogenomics Approach.
Johanns TM, Ward JP, Miller CA, Wilson C, Kobayashi DK, Bender D, Fu Y, Alexandrov A, Mardis ER, Artyomov MN, Schreiber RD, Dunn GP. Johanns TM, et al. Among authors: miller ca. Cancer Immunol Res. 2016 Dec;4(12):1007-1015. doi: 10.1158/2326-6066.CIR-16-0156. Epub 2016 Oct 31. Cancer Immunol Res. 2016. PMID: 27799140 Free PMC article.
Cancer Immunogenomics: Computational Neoantigen Identification and Vaccine Design.
Hundal J, Miller CA, Griffith M, Griffith OL, Walker J, Kiwala S, Graubert A, McMichael J, Coffman A, Mardis ER. Hundal J, et al. Among authors: miller ca. Cold Spring Harb Symp Quant Biol. 2016;81:105-111. doi: 10.1101/sqb.2016.81.030726. Epub 2017 Apr 7. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28389595 Free PMC article. Review.
Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma.
Johanns TM, Miller CA, Liu CJ, Perrin RJ, Bender D, Kobayashi DK, Campian JL, Chicoine MR, Dacey RG, Huang J, Fritsch EF, Gillanders WE, Artyomov MN, Mardis ER, Schreiber RD, Dunn GP. Johanns TM, et al. Among authors: miller ca. Oncoimmunology. 2019 Jan 25;8(4):e1561106. doi: 10.1080/2162402X.2018.1561106. eCollection 2019. Oncoimmunology. 2019. PMID: 30906654 Free PMC article.
pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.
Hundal J, Kiwala S, McMichael J, Miller CA, Xia H, Wollam AT, Liu CJ, Zhao S, Feng YY, Graubert AP, Wollam AZ, Neichin J, Neveau M, Walker J, Gillanders WE, Mardis ER, Griffith OL, Griffith M. Hundal J, et al. Among authors: miller ca. Cancer Immunol Res. 2020 Mar;8(3):409-420. doi: 10.1158/2326-6066.CIR-19-0401. Epub 2020 Jan 6. Cancer Immunol Res. 2020. PMID: 31907209 Free PMC article.
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.
Xia H, McMichael J, Becker-Hapak M, Onyeador OC, Buchli R, McClain E, Pence P, Supabphol S, Richters MM, Basu A, Ramirez CA, Puig-Saus C, Cotto KC, Freshour SL, Hundal J, Kiwala S, Goedegebuure SP, Johanns TM, Dunn GP, Ribas A, Miller CA, Gillanders WE, Fehniger TA, Griffith OL, Griffith M. Xia H, et al. Among authors: miller ca. Sci Immunol. 2023 Apr 14;8(82):eabg2200. doi: 10.1126/sciimmunol.abg2200. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027480 Free PMC article.
Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology.
Panni UY, Chen MY, Zhang F, Cullinan DR, Li L, James CA, Zhang X, Rogers S, Alarcon A, Baer JM, Zhang D, Gao F, Miller CA, Gong Q, Lim KH, DeNardo DG, Goedegebuure SP, Gillanders WE, Hawkins WG. Panni UY, et al. Among authors: miller ca. Cancer Immunol Immunother. 2023 Aug;72(8):2813-2827. doi: 10.1007/s00262-023-03463-x. Epub 2023 May 13. Cancer Immunol Immunother. 2023. PMID: 37179276 Free PMC article.
1,347 results