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53 results

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Page 1
Ferroptosis regulates hemolysis in stored murine and human red blood cells.
D'Alessandro A, Keele GR, Hay AM, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman SH, Spitalnik SL, Roubinian NH, Norris PJ, Busch MP, Page GP, Stockwell B, Churchill GA, Zimring JC. D'Alessandro A, et al. Among authors: earley ej. Blood. 2024 Nov 14:blood.2024026109. doi: 10.1182/blood.2024026109. Online ahead of print. Blood. 2024. PMID: 39541586
Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.
Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'Alessandro A. Nemkov T, et al. Among authors: earley ej. Blood. 2024 Feb 1;143(5):456-472. doi: 10.1182/blood.2023022052. Blood. 2024. PMID: 37976448
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Nemkov T, et al. Among authors: earley ej. Blood. 2024 Jun 13;143(24):2517-2533. doi: 10.1182/blood.2024023983. Blood. 2024. PMID: 38513237
Increased exercise tolerance in humanized G6PD deficient mice.
Cendali FI, Lisk C, Dzieciatkowska M, LaCroix IS, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow E, Darehshouri A, Dziewulska K, Buehler PW, Norris PJ, Deng X, Busch MP, Earley EJ, Page GP, Hansen KC, Zimring JC, Irwin D, Nemkov T, D'Alessandro A. Cendali FI, et al. Among authors: earley ej. Blood Adv. 2024 Nov 8:bloodadvances.2024013968. doi: 10.1182/bloodadvances.2024013968. Online ahead of print. Blood Adv. 2024. PMID: 39514761
Genetic polymorphisms and expression of Rhesus blood group RHCE are associated with 2,3-bisphosphoglycerate in humans at high altitude.
D'Alessandro A, Earley EJ, Nemkov T, Stephenson D, Dzieciatkowska M, Hansen KC, Minetti G, Champigneulle B, Stauffer E, Pichon A, Furian M, Verges S, Kleinman S, Norris PJ, Busch MP, Page GP, Kaestner L. D'Alessandro A, et al. Among authors: earley ej. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2315930120. doi: 10.1073/pnas.2315930120. Epub 2023 Dec 26. Proc Natl Acad Sci U S A. 2024. PMID: 38147558 Free PMC article.
Large genome-wide association study identifies three novel risk variants for restless legs syndrome.
Didriksen M, Nawaz MS, Dowsett J, Bell S, Erikstrup C, Pedersen OB, Sørensen E, Jennum PJ, Burgdorf KS, Burchell B, Butterworth AS, Soranzo N, Rye DB, Trotti LM, Saini P, Stefansdottir L, Magnusson SH, Thorleifsson G, Sigmundsson T, Sigurdsson AP, Van Den Hurk K, Quee F, Tanck MWT, Ouwehand WH, Roberts DJ, Earley EJ, Busch MP, Mast AE, Page GP, Danesh J, Di Angelantonio E, Stefansson H, Ullum H, Stefansson K. Didriksen M, et al. Among authors: earley ej. Commun Biol. 2020 Nov 25;3(1):703. doi: 10.1038/s42003-020-01430-1. Commun Biol. 2020. PMID: 33239738 Free PMC article.
Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci.
Earley EJ, Kelly S, Fang F, Alencar CS, Rodrigues DOW, Soares Cruz DT, Flanagan JM, Ware RE, Zhang X, Gordeuk V, Gladwin M, Zhang Y, Nouraie M, Nekhai S, Sabino E, Custer B, Dinardo C, Page GP; International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS-III) and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Earley EJ, et al. Br J Haematol. 2023 Apr;201(2):343-352. doi: 10.1111/bjh.18637. Epub 2023 Jan 5. Br J Haematol. 2023. PMID: 36602125 Free PMC article.
53 results