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165 results

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Page 1
Ferroptosis regulates hemolysis in stored murine and human red blood cells.
D'Alessandro A, Keele GR, Hay AM, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman SH, Spitalnik SL, Roubinian NH, Norris PJ, Busch MP, Page GP, Stockwell B, Churchill GA, Zimring JC. D'Alessandro A, et al. Among authors: page gp. Blood. 2024 Nov 14:blood.2024026109. doi: 10.1182/blood.2024026109. Online ahead of print. Blood. 2024. PMID: 39541586
Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.
Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'Alessandro A. Nemkov T, et al. Among authors: page gp. Blood. 2024 Feb 1;143(5):456-472. doi: 10.1182/blood.2023022052. Blood. 2024. PMID: 37976448
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Nemkov T, et al. Among authors: page gp. Blood. 2024 Jun 13;143(24):2517-2533. doi: 10.1182/blood.2024023983. Blood. 2024. PMID: 38513237
Increased exercise tolerance in humanized G6PD deficient mice.
Cendali FI, Lisk C, Dzieciatkowska M, LaCroix IS, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow E, Darehshouri A, Dziewulska K, Buehler PW, Norris PJ, Deng X, Busch MP, Earley EJ, Page GP, Hansen KC, Zimring JC, Irwin D, Nemkov T, D'Alessandro A. Cendali FI, et al. Among authors: page gp. Blood Adv. 2024 Nov 8:bloodadvances.2024013968. doi: 10.1182/bloodadvances.2024013968. Online ahead of print. Blood Adv. 2024. PMID: 39514761
Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics.
D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). D'Alessandro A, et al. Transfusion. 2019 Jan;59(1):89-100. doi: 10.1111/trf.14979. Epub 2018 Oct 24. Transfusion. 2019. PMID: 30353560 Free PMC article.
Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity.
D'Alessandro A, Fu X, Kanias T, Reisz JA, Culp-Hill R, Guo Y, Gladwin MT, Page G, Kleinman S, Lanteri M, Stone M, Busch MP, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). D'Alessandro A, et al. Haematologica. 2021 May 1;106(5):1290-1302. doi: 10.3324/haematol.2020.246603. Haematologica. 2021. PMID: 32241843 Free PMC article.
Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers.
Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). Stefanoni D, et al. Among authors: page gp. Transfusion. 2020 Jun;60(6):1160-1174. doi: 10.1111/trf.15812. Epub 2020 May 8. Transfusion. 2020. PMID: 32385854 Free PMC article.
Stored RBC metabolism as a function of caffeine levels.
D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). D'Alessandro A, et al. Among authors: page gp. Transfusion. 2020 Jun;60(6):1197-1211. doi: 10.1111/trf.15813. Epub 2020 May 11. Transfusion. 2020. PMID: 32394461 Free PMC article. Clinical Trial.
Blood donor obesity is associated with changes in red blood cell metabolism and susceptibility to hemolysis in cold storage and in response to osmotic and oxidative stress.
Hazegh K, Fang F, Bravo MD, Tran JQ, Muench MO, Jackman RP, Roubinian N, Bertolone L, DʼAlessandro A, Dumont L, Page GP, Kanias T. Hazegh K, et al. Among authors: page gp. Transfusion. 2021 Feb;61(2):435-448. doi: 10.1111/trf.16168. Epub 2020 Nov 4. Transfusion. 2021. PMID: 33146433 Free PMC article.
165 results