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Page 1
Ferroptosis regulates hemolysis in stored murine and human red blood cells.
D'Alessandro A, Keele GR, Hay AM, Nemkov T, Earley EJ, Stephenson D, Vincent M, Deng X, Stone M, Dzieciatkowska M, Hansen KC, Kleinman SH, Spitalnik SL, Roubinian NH, Norris PJ, Busch MP, Page GP, Stockwell B, Churchill GA, Zimring JC. D'Alessandro A, et al. Among authors: stone m. Blood. 2024 Nov 14:blood.2024026109. doi: 10.1182/blood.2024026109. Online ahead of print. Blood. 2024. PMID: 39541586
Sphingosine 1-phosphate has a negative effect on RBC storage quality.
Hay A, Nemkov T, Gamboni F, Dzieciatkowska M, Key A, Galbraith M, Bartsch K, Sun K, Xia Y, Stone M, Busch MP, Norris PJ, Zimring JC, D'Alessandro A. Hay A, et al. Among authors: stone m. Blood Adv. 2023 Apr 25;7(8):1379-1393. doi: 10.1182/bloodadvances.2022008936. Blood Adv. 2023. PMID: 36469038 Free PMC article.
Regulation of kynurenine metabolism by blood donor genetics and biology impacts red cell hemolysis in vitro and in vivo.
Nemkov T, Stephenson D, Erickson C, Dzieciatkowska M, Key A, Moore A, Earley EJ, Page GP, Lacroix IS, Stone M, Deng X, Raife T, Kleinman S, Zimring JC, Roubinian N, Hansen KC, Busch MP, Norris PJ, D'Alessandro A. Nemkov T, et al. Among authors: stone m. Blood. 2024 Feb 1;143(5):456-472. doi: 10.1182/blood.2023022052. Blood. 2024. PMID: 37976448
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay A, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman S, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian N, Page GP, Zimring JC, Arduini A, D'Alessandro A. Nemkov T, et al. Among authors: stone m. Blood. 2024 Jun 13;143(24):2517-2533. doi: 10.1182/blood.2024023983. Blood. 2024. PMID: 38513237
Biological and genetic determinants of glycolysis: Phosphofructokinase isoforms boost energy status of stored red blood cells and transfusion outcomes.
Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman ZB, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Nemkov T, et al. Among authors: stone m. Cell Metab. 2024 Sep 3;36(9):1979-1997.e13. doi: 10.1016/j.cmet.2024.06.007. Epub 2024 Jul 3. Cell Metab. 2024. PMID: 38964323
Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics.
D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS-III). D'Alessandro A, et al. Among authors: stone m. Transfusion. 2019 Jan;59(1):89-100. doi: 10.1111/trf.14979. Epub 2018 Oct 24. Transfusion. 2019. PMID: 30353560 Free PMC article.
Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity.
D'Alessandro A, Fu X, Kanias T, Reisz JA, Culp-Hill R, Guo Y, Gladwin MT, Page G, Kleinman S, Lanteri M, Stone M, Busch MP, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). D'Alessandro A, et al. Among authors: stone m. Haematologica. 2021 May 1;106(5):1290-1302. doi: 10.3324/haematol.2020.246603. Haematologica. 2021. PMID: 32241843 Free PMC article.
Impact of taurine on red blood cell metabolism and implications for blood storage.
Bertolone L, Roy MK, Hay AM, Morrison EJ, Stefanoni D, Fu X, Kanias T, Kleinman S, Dumont LJ, Stone M, Nemkov T, Busch MP, Zimring JC, D'Alessandro A. Bertolone L, et al. Among authors: stone m. Transfusion. 2020 Jun;60(6):1212-1226. doi: 10.1111/trf.15810. Epub 2020 Apr 27. Transfusion. 2020. PMID: 32339326 Free PMC article.
Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers.
Stefanoni D, Fu X, Reisz JA, Kanias T, Nemkov T, Page GP, Dumont L, Roubinian N, Stone M, Kleinman S, Busch M, Zimring JC, D'Alessandro A; Recipient Epidemiology and Donor Evaluation Study-III (REDS III). Stefanoni D, et al. Among authors: stone m. Transfusion. 2020 Jun;60(6):1160-1174. doi: 10.1111/trf.15812. Epub 2020 May 8. Transfusion. 2020. PMID: 32385854 Free PMC article.
3,167 results