Huang XY - Search Results

1

Architecture and activation of single-pass transmembrane receptor guanylyl cyclase.

Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY. Liu S, et al. Among authors: huang xy. Nat Struct Mol Biol. 2024 Nov 14. doi: 10.1038/s41594-024-01426-z. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 39543315

2

Structural basis and mechanism of activation of two different families of G proteins by the same GPCR.

Alegre KO, Paknejad N, Su M, Lou JS, Huang J, Jordan KD, Eng ET, Meyerson JR, Hite RK, Huang XY. Alegre KO, et al. Among authors: huang xy, huang j. Nat Struct Mol Biol. 2021 Nov;28(11):936-944. doi: 10.1038/s41594-021-00679-2. Epub 2021 Nov 10. Nat Struct Mol Biol. 2021. PMID: 34759376 Free PMC article.

3

Structures of β₁-adrenergic receptor in complex with Gs and ligands of different efficacies.

Su M, Paknejad N, Zhu L, Wang J, Do HN, Miao Y, Liu W, Hite RK, Huang XY. Su M, et al. Among authors: huang xy. Nat Commun. 2022 Jul 14;13(1):4095. doi: 10.1038/s41467-022-31823-1. Nat Commun. 2022. PMID: 35835792 Free PMC article.

4

Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β₁-Adrenergic Receptor.

Su M, Zhu L, Zhang Y, Paknejad N, Dey R, Huang J, Lee MY, Williams D, Jordan KD, Eng ET, Ernst OP, Meyerson JR, Hite RK, Walz T, Liu W, Huang XY. Su M, et al. Among authors: huang xy, huang j. Mol Cell. 2020 Oct 1;80(1):59-71.e4. doi: 10.1016/j.molcel.2020.08.001. Epub 2020 Aug 19. Mol Cell. 2020. PMID: 32818430 Free PMC article.

5

Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate.

Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY. Liu S, et al. Among authors: huang xy. Nat Commun. 2022 Feb 8;13(1):731. doi: 10.1038/s41467-022-28417-2. Nat Commun. 2022. PMID: 35136060 Free PMC article.

6

Structural basis of agonist specificity of α_1A-adrenergic receptor.

Su M, Wang J, Xiang G, Do HN, Levitz J, Miao Y, Huang XY. Su M, et al. Among authors: huang xy. Nat Commun. 2023 Aug 10;14(1):4819. doi: 10.1038/s41467-023-40524-2. Nat Commun. 2023. PMID: 37563160 Free PMC article.

7

Distinct binding conformations of epinephrine with α- and β-adrenergic receptors.

Lou JS, Su M, Wang J, Do HN, Miao Y, Huang XY. Lou JS, et al. Among authors: huang xy. Exp Mol Med. 2024 Sep;56(9):1952-1966. doi: 10.1038/s12276-024-01296-x. Epub 2024 Sep 2. Exp Mol Med. 2024. PMID: 39218975 Free PMC article.

8

Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state.

Huang J, Chen S, Zhang JJ, Huang XY. Huang J, et al. Among authors: huang xy. Nat Struct Mol Biol. 2013 Apr;20(4):419-25. doi: 10.1038/nsmb.2504. Epub 2013 Feb 24. Nat Struct Mol Biol. 2013. PMID: 23435379 Free PMC article.

9

Ligand occupancy in crystal structure of β1-adrenergic G protein-coupled receptor.

Huang J, Chen S, Zhang JJ, Huang XY. Huang J, et al. Among authors: huang xy. Nat Struct Mol Biol. 2015 Dec;22(12):942. doi: 10.1038/nsmb.3131. Nat Struct Mol Biol. 2015. PMID: 26643843 No abstract available.

10

Regulation, Signaling, and Physiological Functions of G-Proteins.

Syrovatkina V, Alegre KO, Dey R, Huang XY. Syrovatkina V, et al. Among authors: huang xy. J Mol Biol. 2016 Sep 25;428(19):3850-68. doi: 10.1016/j.jmb.2016.08.002. Epub 2016 Aug 8. J Mol Biol. 2016. PMID: 27515397 Free PMC article. Review.

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