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Closing the Design-Make-Test-Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability.
Santisteban Valencia Z, Kingston J, Miljković F, Rowbottom H, Mann N, Davies S, Ekblad M, Di Castro S, Kwapień K, Malmerberg E, Friis SD, Lundbäck T, Leek T, Wernevik J. Santisteban Valencia Z, et al. Among authors: friis sd. J Med Chem. 2024 Nov 8. doi: 10.1021/acs.jmedchem.4c01642. Online ahead of print. J Med Chem. 2024. PMID: 39514447
Experimentally validated modeling of dynamic drug-hERG channel interactions reproducing the binding mechanisms and its importance in action potential duration.
Escobar F, Friis S, Adly N, Brinkwirth N, Gomis-Tena J, Saiz J, Klaerke DA, Stoelzle-Feix S, Romero L. Escobar F, et al. Among authors: friis s. Comput Methods Programs Biomed. 2024 Sep;254:108293. doi: 10.1016/j.cmpb.2024.108293. Epub 2024 Jun 22. Comput Methods Programs Biomed. 2024. PMID: 38936153 Free article.
Have the recent advancements in cancer therapy and survival benefitted patients of all age groups across the Nordic countries? NORDCAN survival analyses 2002-2021.
Johansson ALV, Kønig SM, Larønningen S, Engholm G, Kroman N, Seppä K, Malila N, Steig BÁ, Gudmundsdóttir EM, Ólafsdóttir EJ, Lundberg FE, Andersson TM, Lambert PC, Lambe M, Pettersson D, Aagnes B, Friis S, Storm H. Johansson ALV, et al. Among authors: friis s. Acta Oncol. 2024 Apr 10;63:179-191. doi: 10.2340/1651-226X.2024.35094. Acta Oncol. 2024. PMID: 38597666 Free PMC article.
617 results