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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins.
Ackloo S, Li F, Szewczyk M, Seitova A, Loppnau P, Zeng H, Xu J, Ahmad S, Arnautova YA, Baghaie AJ, Beldar S, Bolotokova A, Centrella PA, Chau I, Clark MA, Cuozzo JW, Dehghani-Tafti S, Disch JS, Dong A, Dumas A, Feng JA, Ghiabi P, Gibson E, Gilmer J, Goldman B, Green SR, Guié MA, Guilinger JP, Harms N, Herasymenko O, Houliston S, Hutchinson A, Kearnes S, Keefe AD, Kimani SW, Kramer T, Kutera M, Kwak HA, Lento C, Li Y, Liu J, Loup J, Machado RAC, Mulhern CJ, Perveen S, Righetto GL, Riley P, Shrestha S, Sigel EA, Silva M, Sintchak MD, Slakman BL, Taylor RD, Thompson J, Torng W, Underkoffler C, von Rechenberg M, Walsh RT, Watson I, Wilson DJ, Wolf E, Yadav M, Yazdi AK, Zhang J, Zhang Y, Santhakumar V, Edwards AM, Barsyte-Lovejoy D, Schapira M, Brown PJ, Halabelian L, Arrowsmith CH. Ackloo S, et al. Among authors: wolf e. J Med Chem. 2024 Nov 4. doi: 10.1021/acs.jmedchem.4c02010. Online ahead of print. J Med Chem. 2024. PMID: 39495097
A novel N4,N4-dimethylcytidine in the archaeal ribosome enhances hyperthermophily.
Fluke KA, Dai N, Wolf EJ, Fuchs RT, Ho PS, Talbott V, Elkins L, Tsai YL, Schiltz J, Febvre HP, Czarny R, Robb GB, Corrêa IR Jr, Santangelo TJ. Fluke KA, et al. Among authors: wolf ej. Proc Natl Acad Sci U S A. 2024 Nov 5;121(45):e2405999121. doi: 10.1073/pnas.2405999121. Epub 2024 Oct 29. Proc Natl Acad Sci U S A. 2024. PMID: 39471227
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland M, Hartmann O, Tauch S, Bugter JM, Prieto-Garcia C, Schulte C, Loebbert S, Solvie D, Bitman-Lotan E, Narain A, Jacomin AC, Schuelein-Voelk C, Fuss CT, Pahor N, Ade C, Buck V, Potente M, Li V, Beliu G, Wiegering A, Grossmann T, Eilers M, Wolf E, Maric H, Rosenfeldt M, Maurice MM, Dikic I, Gallant P, Orian A, Diefenbacher ME. Reissland M, et al. Among authors: wolf e. Oncogene. 2024 Dec;43(50):3645-3659. doi: 10.1038/s41388-024-03141-x. Epub 2024 Oct 23. Oncogene. 2024. PMID: 39443725
Oxidative stress initiates hemodynamic change in CKD-induced heart disease.
Sen P, Hamers J, Sittig T, Shashikadze B, d'Ambrosio L, Stöckl JB, Bierschenk S, Zhang H, d'Alessio C, Zandbergen LM, Pauly V, Clauss S, Wolf E, Dendorfer A, Fröhlich T, Merkus D. Sen P, et al. Among authors: wolf e. Basic Res Cardiol. 2024 Oct 15. doi: 10.1007/s00395-024-01085-7. Online ahead of print. Basic Res Cardiol. 2024. PMID: 39404904
2,445 results