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DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency.
Köhnke T, Karigane D, Hilgart E, Fan AC, Kayamori K, Miyauchi M, Collins CT, Suchy FP, Rangavajhula A, Feng Y, Nakauchi Y, Martinez-Montes E, Fowler JL, Loh KM, Nakauchi H, Koldobskiy MA, Feinberg AP, Majeti R. Köhnke T, et al. Among authors: nakauchi h. bioRxiv [Preprint]. 2024 Oct 29:2024.10.26.620318. doi: 10.1101/2024.10.26.620318. bioRxiv. 2024. PMID: 39553934 Free PMC article. Preprint.
Targeted hematopoietic stem cell depletion through SCF-blockade.
Chan YY, Ho PY, Dib C, Swartzrock L, Rayburn M, Willner H, Ko E, Ho K, Down JD, Wilkinson AC, Nakauchi H, Denis M, Cool T, Czechowicz A. Chan YY, et al. Among authors: nakauchi h. Stem Cell Res Ther. 2024 Oct 29;15(1):387. doi: 10.1186/s13287-024-03981-0. Stem Cell Res Ther. 2024. PMID: 39473008 Free PMC article.
Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State.
Yoneyama Y, Zhang RR, Kimura M, Cai Y, Adam M, Parameswaran S, Masaki H, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T. Yoneyama Y, et al. Among authors: nakauchi h. bioRxiv [Preprint]. 2024 Jun 27:2024.06.27.600209. doi: 10.1101/2024.06.27.600209. bioRxiv. 2024. PMID: 38979277 Free PMC article. Preprint.
Disentangling cell-intrinsic and extrinsic factors underlying evolution.
Starr AL, Nishimura T, Igarashi KJ, Funamoto C, Nakauchi H, Fraser HB. Starr AL, et al. Among authors: nakauchi h. bioRxiv [Preprint]. 2024 Aug 4:2024.05.06.592777. doi: 10.1101/2024.05.06.592777. bioRxiv. 2024. PMID: 38798687 Free PMC article. Preprint.
Skin graft with dermis and appendages generated in vivo by cell competition.
Nagano H, Mizuno N, Sato H, Mizutani E, Yanagida A, Kano M, Kasai M, Yamamoto H, Watanabe M, Suchy F, Masaki H, Nakauchi H. Nagano H, et al. Among authors: nakauchi h. Nat Commun. 2024 Apr 29;15(1):3366. doi: 10.1038/s41467-024-47527-7. Nat Commun. 2024. PMID: 38684678 Free PMC article.
Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors.
Suchy FP, Karigane D, Nakauchi Y, Higuchi M, Zhang J, Pekrun K, Hsu I, Fan AC, Nishimura T, Charlesworth CT, Bhadury J, Nishimura T, Wilkinson AC, Kay MA, Majeti R, Nakauchi H. Suchy FP, et al. Among authors: nakauchi h. Nat Biotechnol. 2024 Apr 8:10.1038/s41587-024-02171-w. doi: 10.1038/s41587-024-02171-w. Online ahead of print. Nat Biotechnol. 2024. PMID: 38589662
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells.
Fowler JL, Zheng SL, Nguyen A, Chen A, Xiong X, Chai T, Chen JY, Karigane D, Banuelos AM, Niizuma K, Kayamori K, Nishimura T, Cromer MK, Gonzalez-Perez D, Mason C, Liu DD, Yilmaz L, Miquerol L, Porteus MH, Luca VC, Majeti R, Nakauchi H, Red-Horse K, Weissman IL, Ang LT, Loh KM. Fowler JL, et al. Among authors: nakauchi h. Dev Cell. 2024 May 6;59(9):1110-1131.e22. doi: 10.1016/j.devcel.2024.03.003. Epub 2024 Apr 2. Dev Cell. 2024. PMID: 38569552 Free PMC article.
560 results