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Page 1
DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency.
Köhnke T, Karigane D, Hilgart E, Fan AC, Kayamori K, Miyauchi M, Collins CT, Suchy FP, Rangavajhula A, Feng Y, Nakauchi Y, Martinez-Montes E, Fowler JL, Loh KM, Nakauchi H, Koldobskiy MA, Feinberg AP, Majeti R. Köhnke T, et al. Among authors: nakauchi y. bioRxiv [Preprint]. 2024 Oct 29:2024.10.26.620318. doi: 10.1101/2024.10.26.620318. bioRxiv. 2024. PMID: 39553934 Free PMC article. Preprint.
Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis.
Wang W, Arreola M, Mathews T, DeVilbiss AW, Zhao Z, Martin-Sandoval M, Mohammed A, Benegiamo G, Awani A, Goeminne LJE, Dever DP, Nakauchi Y, Porteus MH, Pavel-Dinu M, Al Herz W, Auwerx J, Morrison SJ, Weinacht KG. Wang W, et al. Among authors: nakauchi y. Blood. 2024 Oct 8:blood.2024024123. doi: 10.1182/blood.2024024123. Online ahead of print. Blood. 2024. PMID: 39378586
A single cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis.
Ediriwickrema A, Nakauchi Y, Fan AC, Köhnke T, Hu X, Luca BA, Kim Y, Ramakrishnan S, Nakamoto M, Karigane D, Linde MH, Azizi A, Newman AM, Gentles AJ, Majeti R. Ediriwickrema A, et al. Among authors: nakauchi y. bioRxiv [Preprint]. 2024 May 10:2024.05.07.592983. doi: 10.1101/2024.05.07.592983. bioRxiv. 2024. PMID: 38766031 Free PMC article. Preprint.
AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML.
Sayitoglu EC, Luca BA, Boss AP, Thomas BC, Freeborn RA, Uyeda MJ, Chen PP, Nakauchi Y, Waichler C, Lacayo N, Bacchetta R, Majeti R, Gentles AJ, Cepika AM, Roncarolo MG. Sayitoglu EC, et al. Among authors: nakauchi y. Leukemia. 2024 Jun;38(6):1246-1255. doi: 10.1038/s41375-024-02255-1. Epub 2024 May 9. Leukemia. 2024. PMID: 38724673 Free PMC article.
Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors.
Suchy FP, Karigane D, Nakauchi Y, Higuchi M, Zhang J, Pekrun K, Hsu I, Fan AC, Nishimura T, Charlesworth CT, Bhadury J, Nishimura T, Wilkinson AC, Kay MA, Majeti R, Nakauchi H. Suchy FP, et al. Among authors: nakauchi y. Nat Biotechnol. 2024 Apr 8:10.1038/s41587-024-02171-w. doi: 10.1038/s41587-024-02171-w. Online ahead of print. Nat Biotechnol. 2024. PMID: 38589662
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency.
Pavel-Dinu M, Gardner CL, Nakauchi Y, Kawai T, Delmonte OM, Palterer B, Bosticardo M, Pala F, Viel S, Malech HL, Ghanim HY, Bode NM, Kurgan GL, Detweiler AM, Vakulskas CA, Neff NF, Sheikali A, Menezes ST, Chrobok J, Hernández González EM, Majeti R, Notarangelo LD, Porteus MH. Pavel-Dinu M, et al. Among authors: nakauchi y. Blood Adv. 2024 Apr 9;8(7):1820-1833. doi: 10.1182/bloodadvances.2023011766. Blood Adv. 2024. PMID: 38096800 Free PMC article.
77 results