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DNA methylation stochasticity is linked to transcriptional variability and identifies convergent epigenetic disruption across genetically-defined subtypes of AML.
Hilgart E, Zhou W, Martinez-Montes E, Idrizi A, Tryggvadottir R, Gondek LP, Majeti R, Ji H, Koldobskiy MA, Feinberg AP. Hilgart E, et al. Among authors: feinberg ap. bioRxiv [Preprint]. 2024 Oct 29:2024.10.26.620422. doi: 10.1101/2024.10.26.620422. bioRxiv. 2024. PMID: 39554147 Free PMC article. Preprint.
DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency.
Köhnke T, Karigane D, Hilgart E, Fan AC, Kayamori K, Miyauchi M, Collins CT, Suchy FP, Rangavajhula A, Feng Y, Nakauchi Y, Martinez-Montes E, Fowler JL, Loh KM, Nakauchi H, Koldobskiy MA, Feinberg AP, Majeti R. Köhnke T, et al. Among authors: feinberg ap. bioRxiv [Preprint]. 2024 Oct 29:2024.10.26.620318. doi: 10.1101/2024.10.26.620318. bioRxiv. 2024. PMID: 39553934 Free PMC article. Preprint.
Exposure to air pollution is associated with DNA methylation changes in sperm.
Schrott R, Feinberg JI, Newschaffer CJ, Hertz-Picciotto I, Croen LA, Fallin MD, Volk HE, Ladd-Acosta C, Feinberg AP. Schrott R, et al. Among authors: feinberg ap. Environ Epigenet. 2024 Feb 8;10(1):dvae003. doi: 10.1093/eep/dvae003. eCollection 2024. Environ Epigenet. 2024. PMID: 38559770 Free PMC article.
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.
Wulfridge P, Davidovich A, Salvador AC, Manno GC, Tryggvadottir R, Idrizi A, Huda MN, Bennett BJ, Adams LG, Hansen KD, Threadgill DW, Feinberg AP. Wulfridge P, et al. Among authors: feinberg ap. PLoS Genet. 2023 Oct 23;19(10):e1010997. doi: 10.1371/journal.pgen.1010997. eCollection 2023 Oct. PLoS Genet. 2023. PMID: 37871105 Free PMC article.
Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation.
Ni Q, Ge Z, Li Y, Shatkin G, Fu J, Bera K, Yang Y, Wang Y, Sen A, Wu Y, Vasconcelos ACN, Feinberg AP, Konstantopoulos K, Sun SX. Ni Q, et al. Among authors: feinberg ap. bioRxiv [Preprint]. 2024 Apr 18:2023.08.31.555808. doi: 10.1101/2023.08.31.555808. bioRxiv. 2024. Update in: Cell Rep. 2024 Nov 22;43(12):114992. doi: 10.1016/j.celrep.2024.114992 PMID: 37693593 Free PMC article. Updated. Preprint.
Precision pharmacological reversal of genotype-specific diet-induced metabolic syndrome in mice informed by transcriptional regulation.
Wulfridge P, Davidovich A, Salvador AC, Manno GC, Tryggvadottir R, Idrizi A, Huda MN, Bennett BJ, Adams LG, Hansen KD, Threadgill DW, Feinberg AP. Wulfridge P, et al. Among authors: feinberg ap. bioRxiv [Preprint]. 2023 Apr 28:2023.04.25.538156. doi: 10.1101/2023.04.25.538156. bioRxiv. 2023. Update in: PLoS Genet. 2023 Oct 23;19(10):e1010997. doi: 10.1371/journal.pgen.1010997 PMID: 37163127 Free PMC article. Updated. Preprint.
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