Clark AP - Search Results

1

Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C.

Muncie-Vasic JM, Sinha T, Clark AP, Brower EF, Saucerman JJ, Black BL, Bruneau BG. Muncie-Vasic JM, et al. Among authors: clark ap. bioRxiv [Preprint]. 2024 Nov 1:2024.11.01.621613. doi: 10.1101/2024.11.01.621613. bioRxiv. 2024. PMID: 39554149 Free PMC article. Preprint.

2

Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings.

Lei CL, Clark AP, Clerx M, Wei S, Bloothooft M, de Boer TP, Christini DJ, Krogh-Madsen T, Mirams GR. Lei CL, et al. Among authors: clark ap. bioRxiv [Preprint]. 2024 Jul 24:2024.07.23.604780. doi: 10.1101/2024.07.23.604780. bioRxiv. 2024. PMID: 39091746 Free PMC article. Preprint.

3

Tracking amyotrophic lateral sclerosis disease progression using passively collected smartphone sensor data.

Karas M, Olsen J, Straczkiewicz M, Johnson SA, Burke KM, Iwasaki S, Lahav A, Scheier ZA, Clark AP, Iyer AS, Huang E, Berry JD, Onnela JP. Karas M, et al. Among authors: clark ap. Ann Clin Transl Neurol. 2024 Jun;11(6):1380-1392. doi: 10.1002/acn3.52050. Epub 2024 May 30. Ann Clin Transl Neurol. 2024. PMID: 38816946 Free PMC article.

4

Single-cell ionic current phenotyping elucidates non-canonical features and predictive potential of cardiomyocytes during automated drug experiments.

Clark AP, Wei S, Christini DJ, Krogh-Madsen T. Clark AP, et al. J Physiol. 2024 Oct;602(20):5163-5178. doi: 10.1113/JP285120. Epub 2024 May 15. J Physiol. 2024. PMID: 38747042 Free PMC article.

5

Stem cell-derived cardiomyocyte heterogeneity confounds electrophysiological insights.

Clark AP, Krogh-Madsen T, Christini DJ. Clark AP, et al. J Physiol. 2024 Oct;602(20):5155-5162. doi: 10.1113/JP284618. Epub 2024 May 9. J Physiol. 2024. PMID: 38723234 Review.

6

Single-cell ionic current phenotyping explains stem cell-derived cardiomyocyte action potential morphology.

Clark AP, Wei S, Fullerton K, Krogh-Madsen T, Christini DJ. Clark AP, et al. Am J Physiol Heart Circ Physiol. 2024 May 1;326(5):H1146-H1154. doi: 10.1152/ajpheart.00063.2024. Epub 2024 Mar 15. Am J Physiol Heart Circ Physiol. 2024. PMID: 38488520 Free PMC article.

7

Logic-based modeling of biological networks with Netflux.

Clark AP, Chowkwale M, Paap A, Dang S, Saucerman JJ. Clark AP, et al. bioRxiv [Preprint]. 2024 Nov 13:2024.01.11.575227. doi: 10.1101/2024.01.11.575227. bioRxiv. 2024. PMID: 38293087 Free PMC article. Preprint.

8

Optimization of a cardiomyocyte model illuminates role of increased I_Na,L in repolarization reserve.

Fullerton KE, Clark AP, Krogh-Madsen T, Christini DJ. Fullerton KE, et al. Among authors: clark ap. Am J Physiol Heart Circ Physiol. 2024 Feb 1;326(2):H334-H345. doi: 10.1152/ajpheart.00553.2023. Epub 2023 Dec 1. Am J Physiol Heart Circ Physiol. 2024. PMID: 38038718

9

Rapid ionic current phenotyping (RICP) identifies mechanistic underpinnings of iPSC-CM AP heterogeneity.

Clark AP, Wei S, Fullerton K, Krogh-Madsen T, Christini DJ. Clark AP, et al. bioRxiv [Preprint]. 2023 Aug 18:2023.08.16.553521. doi: 10.1101/2023.08.16.553521. bioRxiv. 2023. PMID: 37645815 Free PMC article. Preprint.

10

Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings.

Clark AP, Clerx M, Wei S, Lei CL, de Boer TP, Mirams GR, Christini DJ, Krogh-Madsen T. Clark AP, et al. Europace. 2023 Aug 2;25(9):euad243. doi: 10.1093/europace/euad243. Europace. 2023. PMID: 37552789 Free PMC article.

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