O'Hagan HM - Search Results

1

PTEN depletion reduces H3K27me3 levels to promote epithelial-to-mesenchymal transition in epithelial colorectal cancer cells.

Ghobashi AH, Kimani JW, Ladaika CA, O'Hagan HM. Ghobashi AH, et al. Among authors: o hagan hm. PLoS One. 2024 Nov 19;19(11):e0313769. doi: 10.1371/journal.pone.0313769. eCollection 2024. PLoS One. 2024. PMID: 39561122 Free PMC article.

2

LSD1 inhibition attenuates targeted therapy-induced lineage plasticity in BRAF ^V600E colorectal cancer.

Ladaika CA, Chakraborty A, Masood A, Hostetter G, Yi JM, O'Hagan HM. Ladaika CA, et al. Among authors: o hagan hm. bioRxiv [Preprint]. 2024 Oct 29:2024.10.25.620306. doi: 10.1101/2024.10.25.620306. bioRxiv. 2024. PMID: 39554172 Free PMC article. Preprint.

3

Tumor-intrinsic role of ICAM-1 in driving metastatic progression of triple-negative breast cancer through direct interaction with EGFR.

Kang JH, Uddin N, Kim S, Zhao Y, Yoo KC, Kim MJ, Hong SA, Bae S, Lee JY, Shin I, Jin YW, O'Hagan HM, Yi JM, Lee SJ. Kang JH, et al. Among authors: o hagan hm. Mol Cancer. 2024 Oct 16;23(1):230. doi: 10.1186/s12943-024-02150-4. Mol Cancer. 2024. PMID: 39415210 Free PMC article.

4

LSD1 and CoREST2 Potentiate STAT3 Activity to Promote Enteroendocrine Cell Differentiation in Mucinous Colorectal Cancer.

Ladaika CA, Ghobashi AH, Boulton WC, Miller SA, O'Hagan HM. Ladaika CA, et al. Among authors: o hagan hm. Cancer Res. 2024 Oct 4. doi: 10.1158/0008-5472.CAN-24-0788. Online ahead of print. Cancer Res. 2024. PMID: 39365378

5

Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2.

Wang W, Zhou Y, Wang J, Zhang S, Ozes A, Gao H, Fang F, Wang Y, Chu X, Liu Y, Wan J, Mitra AK, O'Hagan HM, Nephew KP. Wang W, et al. Among authors: o hagan hm. Mol Cancer Ther. 2024 Nov 4;23(11):1666-1679. doi: 10.1158/1535-7163.MCT-23-0314. Mol Cancer Ther. 2024. PMID: 39039946

6

Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors.

Ghobashi AH, Lanzloth R, Ladaika CA, Masood A, O'Hagan HM. Ghobashi AH, et al. Among authors: o hagan hm. Cancers (Basel). 2024 May 28;16(11):2040. doi: 10.3390/cancers16112040. Cancers (Basel). 2024. PMID: 38893159 Free PMC article.

7

Single-cell multi-omics reveals insights into differentiation of rare cell types in mucinous colorectal cancer.

Ladaika CA, Ghobashi AH, Boulton WC, Miller SA, O'Hagan HM. Ladaika CA, et al. Among authors: o hagan hm. bioRxiv [Preprint]. 2024 Feb 5:2024.02.01.578409. doi: 10.1101/2024.02.01.578409. bioRxiv. 2024. PMID: 38370733 Free PMC article. Preprint.

8

Single-cell profiling reveals the impact of genetic alterations on the differentiation of inflammation-induced colon tumors.

Ghobashi AH, Lanzloth R, Ladaika CA, O'Hagan HM. Ghobashi AH, et al. Among authors: o hagan hm. bioRxiv [Preprint]. 2023 Dec 2:2023.11.30.569463. doi: 10.1101/2023.11.30.569463. bioRxiv. 2023. Update in: Cancers (Basel). 2024 May 28;16(11):2040. doi: 10.3390/cancers16112040 PMID: 38077052 Free PMC article. Updated. Preprint.

9

Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer.

Ghobashi AH, Vuong TT, Kimani JW, Ladaika CA, Hollenhorst PC, O'Hagan HM. Ghobashi AH, et al. Among authors: o hagan hm. iScience. 2023 Aug 16;26(9):107630. doi: 10.1016/j.isci.2023.107630. eCollection 2023 Sep 15. iScience. 2023. PMID: 37670785 Free PMC article.

10

Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer.

Ghobashi AH, Vuong TT, Kimani JW, O'Hagan HM. Ghobashi AH, et al. Among authors: o hagan hm. bioRxiv [Preprint]. 2023 Feb 4:2023.01.31.526429. doi: 10.1101/2023.01.31.526429. bioRxiv. 2023. Update in: iScience. 2023 Aug 16;26(9):107630. doi: 10.1016/j.isci.2023.107630 PMID: 36778289 Free PMC article. Updated. Preprint.

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