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Identification of Benzothiazoles Bearing 1,3,4-Thiadiazole as Antiproliferative Hybrids Targeting VEGFR-2 and BRAF Kinase: Design, Synthesis, BIO Evaluation and In Silico Study.
Ewes WA, Tawfik SS, Almatary AM, Ahmad Bhat M, El-Shafey HW, Mohamed AAB, Haikal A, El-Magd MA, Elgazar AA, Balaha M, Hamdi A. Ewes WA, et al. Among authors: el shafey hw. Molecules. 2024 Jul 4;29(13):3186. doi: 10.3390/molecules29133186. Molecules. 2024. PMID: 38999138 Free PMC article.
Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in silico insights.
Hamdi A, Yaseen M, Ewes WA, Bhat MA, Ziedan NI, El-Shafey HW, Mohamed AAB, Elnagar MR, Haikal A, Othman DIA, Elgazar AA, Abusabaa AHA, Abdelrahman KS, Soltan OM, Elbadawi MM. Hamdi A, et al. Among authors: el shafey hw. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2231170. doi: 10.1080/14756366.2023.2231170. J Enzyme Inhib Med Chem. 2023. PMID: 37470409 Free PMC article.
New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study.
Al-Sanea MM, Hamdi A, Mohamed AAB, El-Shafey HW, Moustafa M, Elgazar AA, Eldehna WM, Ur Rahman H, Parambi DGT, Elbargisy RM, Selim S, Bukhari SNA, Magdy Hendawy O, Tawfik SS. Al-Sanea MM, et al. Among authors: el shafey hw. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2166036. doi: 10.1080/14756366.2023.2166036. J Enzyme Inhib Med Chem. 2023. PMID: 36691927 Free PMC article.