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Adipose tissue retains an epigenetic memory of obesity after weight loss.
Hinte LC, Castellano-Castillo D, Ghosh A, Melrose K, Gasser E, Noé F, Massier L, Dong H, Sun W, Hoffmann A, Wolfrum C, Rydén M, Mejhert N, Blüher M, von Meyenn F. Hinte LC, et al. Among authors: ryden m. Nature. 2024 Nov 18. doi: 10.1038/s41586-024-08165-7. Online ahead of print. Nature. 2024. PMID: 39558077
Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health.
Lecoutre S, Maqdasy S, Rizo-Roca D, Renzi G, Vlassakev I, Alaeddine LM, Higos R, Jalkanen J, Zhong J, Zareifi DS, Frendo-Cumbo S, Massier L, Hodek O, Juvany M, Moritz T, de Castro Barbosa T, Omar-Hmeadi M, López-Yus M, Merabtene F, Abatan JB, Marcelin G, El Hachem EJ, Rouault C, Bergo MO, Petrus P, Zierath JR, Clément K, Krook A, Mejhert N, Rydén M. Lecoutre S, et al. Among authors: ryden m. Nat Metab. 2024 Jul;6(7):1329-1346. doi: 10.1038/s42255-024-01083-y. Epub 2024 Jul 15. Nat Metab. 2024. PMID: 39009762 Free PMC article.
The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adipose.
Mashayekhi M, Sheng Q, Bailin SS, Massier L, Zhong J, Shi M, Wanjalla CN, Wang TJ, Ikizler TA, Niswender KD, Gabriel CL, Palacios J, Turgeon-Jones R, Reynolds CF, Luther JM, Brown NJ, Das S, Dahlman I, Mosley JD, Koethe JR, Rydén M, Bachmann KN, Shah RV. Mashayekhi M, et al. Among authors: ryden m. Obesity (Silver Spring). 2024 Aug;32(8):1526-1540. doi: 10.1002/oby.24064. Epub 2024 Jul 5. Obesity (Silver Spring). 2024. PMID: 38967296
304 results