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Page 1
Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.
Blanco E, Camps C, Bahal S, Kerai MD, Ferla MP, Rochussen AM, Handel AE, Golwala ZM, Spiridou Goncalves H, Kricke S, Klein F, Zhang F, Zinghirino F, Evans G, Keane TM, Lizot S, Kusters MAA, Iro MA, Patel SV, Morris EC, Burns SO, Radcliffe R, Vasudevan P, Price A, Gillham O, Valdebenito GE, Stewart GS, Worth A, Adams SP, Duchen M, André I, Adams DJ, Santili G, Gilmour KC, Holländer GA, Davies EG, Taylor JC, Griffiths GM, Thrasher AJ, Dhalla F, Kreins AY. Blanco E, et al. Among authors: handel ae. J Exp Med. 2025 Jan 6;222(1):e20220979. doi: 10.1084/jem.20220979. Epub 2024 Nov 19. J Exp Med. 2025. PMID: 39560673
Novel risk loci in LGI1-antibody encephalitis: genome-wide association study discovery and validation cohorts.
Binks SNM, Elliott KS, Muñiz-Castrillo S, Gilbert E, Kawasaki de Araujo T, Harper AR, Brown AC, Chong AY, Band G, Peris Sempere V, Pinto AL, Costantino F, Rayner NW, Mentzer AJ, Delanty N, Rogemond V, Picard G, Handel AE, Melzer N, Titulaer MJ, Lee ST, Leypoldt F, Kuhlenbaeumer G, Honnorat J, Mignot E, Cavelleri GL, Knight JC, Irani SR. Binks SNM, et al. Among authors: handel ae. Brain. 2024 Oct 26:awae349. doi: 10.1093/brain/awae349. Online ahead of print. Brain. 2024. PMID: 39454566
Fatigue predicts quality of life after leucine-rich glioma-inactivated 1-antibody encephalitis.
Binks SNM, Veldsman M, Handel AE, Jacob S, Maddison P, Coebergh J, Michael S, Ramanathan S, Easton A, Nissen MS, Leite MI, Okai D, Blaabjerg M, Husain M, Irani SR. Binks SNM, et al. Among authors: handel ae. Ann Clin Transl Neurol. 2024 Apr;11(4):1053-1058. doi: 10.1002/acn3.52006. Epub 2024 Feb 1. Ann Clin Transl Neurol. 2024. PMID: 38303486 Free PMC article.
Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells.
Klein F, Veiga-Villauriz C, Börsch A, Maio S, Palmer S, Dhalla F, Handel AE, Zuklys S, Calvo-Asensio I, Musette L, Deadman ME, White AJ, Lucas B, Anderson G, Holländer GA. Klein F, et al. Among authors: handel ae. Nat Commun. 2023 Jul 10;14(1):4071. doi: 10.1038/s41467-023-39722-9. Nat Commun. 2023. PMID: 37429879 Free PMC article.
Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis.
Al-Diwani A, Theorell J, Damato V, Bull J, McGlashan N, Green E, Kienzler AK, Harrison R, Hassanali T, Campo L, Browne M, Easton A, Soleymani Majd H, Tenaka K, Iorio R, Dale RC, Harrison P, Geddes J, Quested D, Sharp D, Lee ST, Nauen DW, Makuch M, Lennox B, Fowler D, Sheerin F, Waters P, Leite MI, Handel AE, Irani SR. Al-Diwani A, et al. Among authors: handel ae. Brain. 2022 Aug 27;145(8):2742-2754. doi: 10.1093/brain/awac088. Brain. 2022. PMID: 35680425 Free PMC article.
80 results