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The Pfam protein families database: embracing AI/ML.
Paysan-Lafosse T, Andreeva A, Blum M, Chuguransky SR, Grego T, Pinto BL, Salazar GA, Bileschi ML, Llinares-López F, Meng-Papaxanthos L, Colwell LJ, Grishin NV, Schaeffer RD, Clementel D, Tosatto SCE, Sonhammer E, Wood V, Bateman A. Paysan-Lafosse T, et al. Among authors: grishin nv. Nucleic Acids Res. 2024 Nov 14:gkae997. doi: 10.1093/nar/gkae997. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39540428
Identification of FDA-approved drugs that induce heart regeneration in mammals.
Ahmed MS, Nguyen NUN, Nakada Y, Hsu CC, Farag A, Lam NT, Wang P, Thet S, Menendez-Montes I, Elhelaly WM, Lou X, Secco I, Tomczyk M, Zentilin L, Pei J, Cui M, Dos Santos M, Liu X, Liu Y, Zaha D, Walcott G, Tomchick DR, Xing C, Zhang CC, Grishin NV, Giacca M, Zhang J, Sadek HA. Ahmed MS, et al. Among authors: grishin nv. Nat Cardiovasc Res. 2024 Mar;3(3):372-388. doi: 10.1038/s44161-024-00450-y. Epub 2024 Mar 11. Nat Cardiovasc Res. 2024. PMID: 39183959 Free PMC article.
Assessing predictions on fitness effects of missense variants in HMBS in CAGI6.
Zhang J, Kinch L, Katsonis P, Lichtarge O, Jagota M, Song YS, Sun Y, Shen Y, Kuru N, Dereli O, Adebali O, Alladin MA, Pal D, Capriotti E, Turina MP, Savojardo C, Martelli PL, Babbi G, Casadio R, Pucci F, Rooman M, Cia G, Tsishyn M, Strokach A, Hu Z, van Loggerenberg W, Roth FP, Radivojac P, Brenner SE, Cong Q, Grishin NV. Zhang J, et al. Among authors: grishin nv. Hum Genet. 2024 Aug 7. doi: 10.1007/s00439-024-02680-3. Online ahead of print. Hum Genet. 2024. PMID: 39110250
Tryptophan fuels MYC-dependent liver tumorigenesis through indole 3-pyruvate synthesis.
Venkateswaran N, Garcia R, Lafita-Navarro MC, Hao YH, Perez-Castro L, Nogueira PAS, Solmonson A, Mender I, Kilgore JA, Fang S, Brown IN, Li L, Parks E, Lopes Dos Santos I, Bhaskar M, Kim J, Jia Y, Lemoff A, Grishin NV, Kinch L, Xu L, Williams NS, Shay JW, DeBerardinis RJ, Zhu H, Conacci-Sorrell M. Venkateswaran N, et al. Among authors: grishin nv. Nat Commun. 2024 May 20;15(1):4266. doi: 10.1038/s41467-024-47868-3. Nat Commun. 2024. PMID: 38769298 Free PMC article.
384 results