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GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter JF, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: palicharla vr. Nat Struct Mol Biol. 2024 Apr;31(4):667-677. doi: 10.1038/s41594-024-01223-8. Epub 2024 Feb 7. Nat Struct Mol Biol. 2024. PMID: 38326651 Free PMC article.
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway.
Hoppe N, Harrison S, Hwang SH, Chen Z, Karelina M, Deshpande I, Suomivuori CM, Palicharla VR, Berry SP, Tschaikner P, Regele D, Covey DF, Stefan E, Marks DS, Reiter J, Dror RO, Evers AS, Mukhopadhyay S, Manglik A. Hoppe N, et al. Among authors: palicharla vr. bioRxiv [Preprint]. 2023 May 24:2023.05.23.540554. doi: 10.1101/2023.05.23.540554. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2024 Apr;31(4):667-677. doi: 10.1038/s41594-024-01223-8 PMID: 37292845 Free PMC article. Updated. Preprint.
A pathogenic variant of TULP3 causes renal and hepatic fibrocystic disease.
Jafari Khamirani H, Palicharla VR, Dastgheib SA, Dianatpour M, Imanieh MH, Tabei SS, Besse W, Mukhopadhyay S, Liem KF Jr. Jafari Khamirani H, et al. Among authors: palicharla vr. Front Genet. 2022 Oct 7;13:1021037. doi: 10.3389/fgene.2022.1021037. eCollection 2022. Front Genet. 2022. PMID: 36276950 Free PMC article.
Cilia-Localized Counterregulatory Signals as Drivers of Renal Cystogenesis.
Walker RV, Maranto A, Palicharla VR, Hwang SH, Mukhopadhyay S, Qian F. Walker RV, et al. Among authors: palicharla vr. Front Mol Biosci. 2022 Jun 23;9:936070. doi: 10.3389/fmolb.2022.936070. eCollection 2022. Front Mol Biosci. 2022. PMID: 35832738 Free PMC article. Review.
Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.
Hwang SH, Somatilaka BN, Badgandi H, Palicharla VR, Walker R, Shelton JM, Qian F, Mukhopadhyay S. Hwang SH, et al. Among authors: palicharla vr. Curr Biol. 2019 Mar 4;29(5):790-802.e5. doi: 10.1016/j.cub.2019.01.047. Epub 2019 Feb 21. Curr Biol. 2019. PMID: 30799239 Free PMC article.
13 results