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Page 1
Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis.
Chen X, Shibu G, Sokolsky BA, Soussana TN, Fisher L, Deochand DK, Dacic M, Mantel I, Ramirez DC, Bell RD, Zhang T, Donlin LT, Goodman SM, Gray NS, Chinenov Y, Fisher RP, Rogatsky I. Chen X, et al. Among authors: shibu g. Sci Transl Med. 2024 Nov 20;16(774):eadq5091. doi: 10.1126/scitranslmed.adq5091. Epub 2024 Nov 20. Sci Transl Med. 2024. PMID: 39565872
Thetis cells induce food-specific Treg cell differentiation and oral tolerance.
Parisotto YF, Cabric V, Park T, Akagbosu B, Zhao Z, Lo Y, Fisher L, Shibu G, Paucar Iza YA, Leslie C, Brown CC. Parisotto YF, et al. Among authors: shibu g. bioRxiv [Preprint]. 2024 May 10:2024.05.08.592952. doi: 10.1101/2024.05.08.592952. bioRxiv. 2024. PMID: 38766121 Free PMC article. Preprint.
Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota.
Akagbosu B, Tayyebi Z, Shibu G, Paucar Iza YA, Deep D, Parisotto YF, Fisher L, Pasolli HA, Thevin V, Elmentaite R, Knott M, Hemmers S, Jahn L, Friedrich C, Verter J, Wang ZM, van den Brink M, Gasteiger G, Grünewald TGP, Marie JC, Leslie C, Rudensky AY, Brown CC. Akagbosu B, et al. Among authors: shibu g. Nature. 2022 Oct;610(7933):752-760. doi: 10.1038/s41586-022-05309-5. Epub 2022 Sep 7. Nature. 2022. PMID: 36070798 Free PMC article.