Hopkinson RJ - Search Results

1

The biochemistry of the carcinogenic alcohol metabolite acetaldehyde.

Thomas LA, Hopkinson RJ. Thomas LA, et al. Among authors: hopkinson rj. DNA Repair (Amst). 2024 Dec;144:103782. doi: 10.1016/j.dnarep.2024.103782. Epub 2024 Nov 5. DNA Repair (Amst). 2024. PMID: 39566398 Free article. Review.

2

Formaldehyde quantification using gas chromatography-mass spectrometry reveals high background environmental formaldehyde levels.

Chothia SY, Emms VL, Thomas LA, Bulman NFA, Monks PS, Cordell RL, Hopkinson RJ. Chothia SY, et al. Among authors: hopkinson rj. Sci Rep. 2024 Sep 4;14(1):20621. doi: 10.1038/s41598-024-71271-z. Sci Rep. 2024. PMID: 39232096 Free PMC article.

3

Friend or foe-maldehyde.

Emms VL, Chothia SY, Hopkinson RJ. Emms VL, et al. Among authors: hopkinson rj. Nat Chem Biol. 2024 Mar;20(3):268-270. doi: 10.1038/s41589-024-01558-9. Nat Chem Biol. 2024. PMID: 38424170 No abstract available.

4

Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism.

John T, Saffoon N, Walsby-Tickle J, Hester SS, Dingler FA, Millington CL, McCullagh JSO, Patel KJ, Hopkinson RJ, Schofield CJ. John T, et al. Among authors: hopkinson rj. Chem Sci. 2024 Jan 15;15(7):2509-2517. doi: 10.1039/d3sc06551k. eCollection 2024 Feb 14. Chem Sci. 2024. PMID: 38362406 Free PMC article.

5

N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells.

Emms VL, Lewis LA, Beja L, Bulman NFA, Pires E, Muskett FW, McCullagh JSO, Swift LP, McHugh PJ, Hopkinson RJ. Emms VL, et al. Among authors: hopkinson rj. Chem Sci. 2023 Sep 15;14(44):12498-12505. doi: 10.1039/d3sc02867d. eCollection 2023 Nov 15. Chem Sci. 2023. PMID: 38020377 Free PMC article.

6

Quantitative detection of formaldehyde using solid phase microextraction gas chromatography-mass spectrometry coupled to cysteamine scavenging.

Chothia SY, Carr M, Monks PS, Cordell RL, Hopkinson RJ. Chothia SY, et al. Among authors: hopkinson rj. Sci Rep. 2023 Sep 5;13(1):14642. doi: 10.1038/s41598-023-41609-0. Sci Rep. 2023. PMID: 37670131 Free PMC article.

7

Formaldehyde reacts with N-terminal proline residues to give bicyclic aminals.

John T, Pires E, Hester SS, Salah E, Hopkinson RJ, Schofield CJ. John T, et al. Among authors: hopkinson rj. Commun Chem. 2023 Jan 13;6(1):12. doi: 10.1038/s42004-022-00801-5. Commun Chem. 2023. PMID: 36698022 Free PMC article.

8

Biochemical and Structural Insights into FIH-Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains.

Saward BG, Leissing TM, Clifton IJ, Tumber A, Timperley CM, Hopkinson RJ, Schofield CJ. Saward BG, et al. Among authors: hopkinson rj. Chembiochem. 2023 Feb 14;24(4):e202200576. doi: 10.1002/cbic.202200576. Epub 2023 Jan 9. Chembiochem. 2023. PMID: 36448355 Free PMC article.

9

Formaldehyde regulates tetrahydrofolate stability and thymidylate synthase catalysis.

Chen X, Chothia SY, Basran J, Hopkinson RJ. Chen X, et al. Among authors: hopkinson rj. Chem Commun (Camb). 2021 Jun 10;57(47):5778-5781. doi: 10.1039/d1cc01425k. Chem Commun (Camb). 2021. PMID: 33997872

10

Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde.

Reinbold R, John T, Spingardi P, Kawamura A, Schofield CJ, Hopkinson RJ. Reinbold R, et al. Among authors: hopkinson rj. Sci Rep. 2020 Oct 21;10(1):17955. doi: 10.1038/s41598-020-74990-1. Sci Rep. 2020. PMID: 33087772 Free PMC article.

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