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Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.
Ye T, Alamgir A, Robertus CM, Colina D, Monticello C, Donahue TC, Hong L, Vincoff S, Goel S, Fekkes P, Camargo LM, Lam K, Heyes J, Putnam D, Alabi CA, Chatterjee P, DeLisa MP. Ye T, et al. Among authors: hong l. bioRxiv [Preprint]. 2024 Nov 11:2024.11.10.622803. doi: 10.1101/2024.11.10.622803. bioRxiv. 2024. PMID: 39605463 Free PMC article. Preprint.
A general temperature-guided language model to design proteins of enhanced stability and activity.
Jiang F, Li M, Dong J, Yu Y, Sun X, Wu B, Huang J, Kang L, Pei Y, Zhang L, Wang S, Xu W, Xin J, Ouyang W, Fan G, Zheng L, Tan Y, Hu Z, Xiong Y, Feng Y, Yang G, Liu Q, Song J, Liu J, Hong L, Tan P. Jiang F, et al. Among authors: hong l. Sci Adv. 2024 Nov 29;10(48):eadr2641. doi: 10.1126/sciadv.adr2641. Epub 2024 Nov 27. Sci Adv. 2024. PMID: 39602544 Free PMC article.
The Reparative Effect of FOXM1 in Pulmonary Disease.
Chen T, Ni M, Wang H, Xue F, Jiang T, Wu X, Li C, Liang S, Hong L, Wu Q. Chen T, et al. Among authors: hong l. Lung. 2024 Nov 27;203(1):1. doi: 10.1007/s00408-024-00773-4. Lung. 2024. PMID: 39601876 Review.
Accelerating Heritability, Genetic Correlation, and Genome-Wide Association Imaging Genetic Analyses in Complex Pedigrees.
Donohue B, Gao S, Nichols TE, Adhikari BM, Ma Y, Jahanshad N, Thompson PM, McMahon FJ, Humphries EM, Burroughs W, Ament SA, Mitchell BD, Ma T, Chen S, Medland SE, Blangero J, Hong LE, Kochunov P. Donohue B, et al. Among authors: hong le. Hum Brain Mapp. 2024 Dec 1;45(17):e70044. doi: 10.1002/hbm.70044. Hum Brain Mapp. 2024. PMID: 39593222 Free PMC article.
3,832 results