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Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer.
Chatterjee SS, Linares JF, Cid-Diaz T, Duran A, Khan MIK, Osrodek M, Brady NJ, Reina-Campos M, Marzio A, Venkadakrishnan VB, Bakht MK, Khani F, Mosquera JM, Robinson BD, Moyer J, Elemento O, Hsieh AC, Goodrich DW, Rickman DS, Beltran H, Moscat J, Diaz-Meco MT. Chatterjee SS, et al. Among authors: brady nj. Nat Commun. 2024 Nov 20;15(1):9755. doi: 10.1038/s41467-024-53874-2. Nat Commun. 2024. PMID: 39567499 Free PMC article.
Distinct mesenchymal cell states mediate prostate cancer progression.
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Socciarelli F, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Dinalankara W, Jere M, Valencia I, Saladino C, Stone J, Unkenholz C, Garner R, Alexanderani MK, Khani F, de Almeida FN, Abate-Shen C, Greenblatt MB, Rickman DS, Barbieri CE, Robinson BD, Marchionni L, Loda M. Pakula H, et al. Among authors: brady nj. Nat Commun. 2024 Jan 8;15(1):363. doi: 10.1038/s41467-023-44210-1. Nat Commun. 2024. PMID: 38191471 Free PMC article.
The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer.
Van Emmenis L, Ku SY, Gayvert K, Branch JR, Brady NJ, Basu S, Russell M, Cyrta J, Vosoughi A, Sailer V, Alnajar H, Dardenne E, Koumis E, Puca L, Robinson BD, Feldkamp MD, Winkis A, Majewski N, Rupnow B, Gottardis MM, Elemento O, Rubin MA, Beltran H, Rickman DS. Van Emmenis L, et al. Among authors: brady nj. Cancer Res Commun. 2023 Aug 3;3(8):1447-1459. doi: 10.1158/2767-9764.CRC-22-0491. eCollection 2023 Aug. Cancer Res Commun. 2023. PMID: 37546702 Free PMC article.
Distinct mesenchymal cell states mediate prostate cancer progression.
Pakula H, Omar M, Carelli R, Pederzoli F, Fanelli GN, Pannellini T, Van Emmenis L, Rodrigues S, Fidalgo-Ribeiro C, Nuzzo PV, Brady NJ, Jere M, Unkenholz C, Alexanderani MK, Khani F, de Almeida FN, Abate-Shen C, Greenblatt MB, Rickman DS, Barbieri CE, Robinson BD, Marchionni L, Loda M. Pakula H, et al. Among authors: brady nj. bioRxiv [Preprint]. 2023 Apr 1:2023.03.29.534769. doi: 10.1101/2023.03.29.534769. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 8;15(1):363. doi: 10.1038/s41467-023-44210-1 PMID: 37034687 Free PMC article. Updated. Preprint.
Defining cellular population dynamics at single-cell resolution during prostate cancer progression.
Germanos AA, Arora S, Zheng Y, Goddard ET, Coleman IM, Ku AT, Wilkinson S, Song H, Brady NJ, Amezquita RA, Zager M, Long A, Yang YC, Bielas JH, Gottardo R, Rickman DS, Huang FW, Ghajar CM, Nelson PS, Sowalsky AG, Setty M, Hsieh AC. Germanos AA, et al. Among authors: brady nj. Elife. 2022 Dec 13;11:e79076. doi: 10.7554/eLife.79076. Elife. 2022. PMID: 36511483 Free PMC article.
JAK inhibition shows two faces in prostate cancer.
Brady NJ, Barbieri CE. Brady NJ, et al. Nat Cancer. 2022 Sep;3(9):1021-1023. doi: 10.1038/s43018-022-00437-3. Nat Cancer. 2022. PMID: 36138136 No abstract available.
A novel source of carbon monoxide for suicide attempt.
Brady NJ, Patel PS, Moayedi S, Sward D. Brady NJ, et al. Undersea Hyperb Med. 2022 Third Quarter;49(3):329-331. doi: 10.22462/05.06.2022.6. Undersea Hyperb Med. 2022. PMID: 36001565
RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer.
Labrecque MP, Brown LG, Coleman IM, Lakely B, Brady NJ, Lee JK, Nguyen HM, Li D, Hanratty B, Haffner MC, Rickman DS, True LD, Lin DW, Lam HM, Alumkal JJ, Corey E, Nelson PS, Morrissey C. Labrecque MP, et al. Among authors: brady nj. Cancer Res. 2021 Sep 15;81(18):4736-4750. doi: 10.1158/0008-5472.CAN-21-0307. Epub 2021 Jul 26. Cancer Res. 2021. PMID: 34312180 Free PMC article.
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