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Page 1
Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer.
Chatterjee SS, Linares JF, Cid-Diaz T, Duran A, Khan MIK, Osrodek M, Brady NJ, Reina-Campos M, Marzio A, Venkadakrishnan VB, Bakht MK, Khani F, Mosquera JM, Robinson BD, Moyer J, Elemento O, Hsieh AC, Goodrich DW, Rickman DS, Beltran H, Moscat J, Diaz-Meco MT. Chatterjee SS, et al. Among authors: venkadakrishnan vb. Nat Commun. 2024 Nov 20;15(1):9755. doi: 10.1038/s41467-024-53874-2. Nat Commun. 2024. PMID: 39567499 Free PMC article.
Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Venkadakrishnan VB, Presser AG, Singh R, Booker MA, Traphagen NA, Weng K, Voss NCE, Mahadevan NR, Mizuno K, Puca L, Idahor O, Ku SY, Bakht MK, Borah AA, Herbert ZT, Tolstorukov MY, Barbie DA, Rickman DS, Brown M, Beltran H. Venkadakrishnan VB, et al. Nat Commun. 2024 Aug 8;15(1):6779. doi: 10.1038/s41467-024-51156-5. Nat Commun. 2024. PMID: 39117665 Free PMC article.
Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer.
Ku SY, Wang Y, Garcia MM, Yamada Y, Mizuno K, Long MD, Rosario S, Chinnam M, Al Assaad M, Puca L, Kim MJ, Bakht MK, Venkadakrishnan VB, Robinson BD, Acosta AM, Wadosky KM, Mosquera JM, Goodrich DW, Beltran H. Ku SY, et al. Among authors: venkadakrishnan vb. J Clin Invest. 2024 Jul 18;134(17):e175217. doi: 10.1172/JCI175217. J Clin Invest. 2024. PMID: 39024561 Free PMC article.
Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes.
Venkadakrishnan VB, Presser AG, Singh R, Booker MA, Traphagen NA, Weng K, Voss NC, Mahadevan NR, Mizuno K, Puca L, Idahor O, Ku SY, Bakht MK, Borah AA, Herbert ZT, Tolstorukov MY, Barbie DA, Rickman DS, Brown M, Beltran H. Venkadakrishnan VB, et al. Res Sq [Preprint]. 2024 Mar 4:rs.3.rs-3935288. doi: 10.21203/rs.3.rs-3935288/v2. Res Sq. 2024. Update in: Nat Commun. 2024 Aug 8;15(1):6779. doi: 10.1038/s41467-024-51156-5 PMID: 38405800 Free PMC article. Updated. Preprint.
Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase.
Rawat C, Ben-Salem S, Singh N, Chauhan G, Rabljenovic A, Vaghela V, Venkadakrishnan VB, Macdonald JD, Dahiya UR, Ghanem Y, Bachour S, Su Y, DePriest AD, Lee S, Muldong M, Kim HT, Kumari S, Valenzuela MM, Zhang D, Hu Q, Cortes Gomez E, Dehm SM, Zoubeidi A, Jamieson CAM, Nicolas M, McKenney J, Willard B, Klein EA, Magi-Galluzzi C, Stauffer SR, Liu S, Heemers HV. Rawat C, et al. Among authors: venkadakrishnan vb. Cancer Res. 2023 Dec 15;83(24):4142-4160. doi: 10.1158/0008-5472.CAN-23-0883. Cancer Res. 2023. PMID: 37801613 Free PMC article.
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer.
Bakht MK, Yamada Y, Ku SY, Venkadakrishnan VB, Korsen JA, Kalidindi TM, Mizuno K, Ahn SH, Seo JH, Garcia MM, Khani F, Elemento O, Long HW, Chaglassian A, Pillarsetty N, Lewis JS, Freedman M, Belanger AP, Nguyen QD, Beltran H. Bakht MK, et al. Among authors: venkadakrishnan vb. Nat Cancer. 2023 May;4(5):699-715. doi: 10.1038/s43018-023-00539-6. Epub 2023 Apr 10. Nat Cancer. 2023. PMID: 37038004 Free PMC article.
CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2.
Li H, Wang Y, Lin K, Venkadakrishnan VB, Bakht M, Shi W, Meng C, Zhang J, Tremble K, Liang X, Song JH, Feng X, Van V, Deng P, Burks JK, Aparicio A, Keyomarsi K, Chen J, Lu Y, Beltran H, Zhao D. Li H, et al. Among authors: venkadakrishnan vb. Cancer Res. 2022 Sep 2;82(17):3088-3101. doi: 10.1158/0008-5472.CAN-22-0631. Cancer Res. 2022. PMID: 35771632 Free PMC article.
Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells.
Bakht MK, Hayward JJ, Shahbazi-Raz F, Skubal M, Tamura R, Stringer KF, Meister D, Venkadakrishnan VB, Xue H, Pillon A, Stover M, Tronchin A, Fifield BA, Mader L, Ku SY, Cheon GJ, Kang KW, Wang Y, Dong X, Beltran H, Grimm J, Porter LA, Trant JF. Bakht MK, et al. Among authors: venkadakrishnan vb. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2025710119. doi: 10.1073/pnas.2025710119. Proc Natl Acad Sci U S A. 2022. PMID: 35064078 Free PMC article.
18 results