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Page 1
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. Saller BS, et al. Among authors: schwemmle m. Immunity. 2024 Nov 15:S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012. Online ahead of print. Immunity. 2024. PMID: 39571574
Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets.
Graaf-Rau A, Schmies K, Breithaupt A, Ciminski K, Zimmer G, Summerfield A, Sehl-Ewert J, Lillie-Jaschniski K, Helmer C, Bielenberg W, Grosse Beilage E, Schwemmle M, Beer M, Harder T. Graaf-Rau A, et al. Among authors: schwemmle m. NPJ Vaccines. 2024 Jul 13;9(1):127. doi: 10.1038/s41541-024-00916-x. NPJ Vaccines. 2024. PMID: 39003272 Free PMC article.
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection.
Moeed A, Thilmany N, Beck F, Puthussery BK, Ortmann N, Haimovici A, Badr MT, Haghighi EB, Boerries M, Öllinger R, Rad R, Kirschnek S, Gentle IE, Donakonda S, Petric PP, Hummel JF, Pfaffendorf E, Zanetta P, Schell C, Schwemmle M, Weber A, Häcker G. Moeed A, et al. Among authors: schwemmle m. Cell Death Differ. 2024 Jul;31(7):924-937. doi: 10.1038/s41418-024-01320-7. Epub 2024 Jun 7. Cell Death Differ. 2024. PMID: 38849575 Free PMC article.
Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level.
Kessler S, Burke B, Andrieux G, Schinköthe J, Hamberger L, Kacza J, Zhan S, Reasoner C, Dutt TS, Kaukab Osman M, Henao-Tamayo M, Staniek J, Villena Ossa JF, Frank DT, Ma W, Ulrich R, Cathomen T, Boerries M, Rizzi M, Beer M, Schwemmle M, Reuther P, Schountz T, Ciminski K. Kessler S, et al. Among authors: schwemmle m. Nat Commun. 2024 May 27;15(1):4500. doi: 10.1038/s41467-024-48934-6. Nat Commun. 2024. PMID: 38802391 Free PMC article.
Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets.
Halwe NJ, Hamberger L, Sehl-Ewert J, Mache C, Schön J, Ulrich L, Calvelage S, Tönnies M, Fuchs J, Bandawane P, Loganathan M, Abbad A, Carreño JM, Bermúdez-González MC, Simon V, Kandeil A, El-Shesheny R, Ali MA, Kayali G, Budt M, Hippenstiel S, Hocke AC, Krammer F, Wolff T, Schwemmle M, Ciminski K, Hoffmann D, Beer M. Halwe NJ, et al. Among authors: schwemmle m. Nat Commun. 2024 Apr 25;15(1):3450. doi: 10.1038/s41467-024-47455-6. Nat Commun. 2024. PMID: 38664395 Free PMC article.
Necroptosis blockade prevents lung injury in severe influenza.
Gautam A, Boyd DF, Nikhar S, Zhang T, Siokas I, Van de Velde LA, Gaevert J, Meliopoulos V, Thapa B, Rodriguez DA, Cai KQ, Yin C, Schnepf D, Beer J, DeAntoneo C, Williams RM, Shubina M, Livingston B, Zhang D, Andrake MD, Lee S, Boda R, Duddupudi AL, Crawford JC, Vogel P, Loch C, Schwemmle M, Fritz LC, Schultz-Cherry S, Green DR, Cuny GD, Thomas PG, Degterev A, Balachandran S. Gautam A, et al. Among authors: schwemmle m. Nature. 2024 Apr;628(8009):835-843. doi: 10.1038/s41586-024-07265-8. Epub 2024 Apr 10. Nature. 2024. PMID: 38600381
Reverse Genetics of Bat Influenza A Viruses.
Kessler S, García-Sastre A, Schwemmle M, Ciminski K. Kessler S, et al. Among authors: schwemmle m. Methods Mol Biol. 2024;2733:75-86. doi: 10.1007/978-1-0716-3533-9_5. Methods Mol Biol. 2024. PMID: 38064027
197 results