Kurmi K - Search Results

1

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing.

Ogawa T, Isik M, Wu Z, Kurmi K, Meng J, Cho S, Lee G, Fernandez-Cardenas LP, Mizunuma M, Blenis J, Haigis MC, Blackwell TK. Ogawa T, et al. Among authors: kurmi k. Mol Cell. 2024 Nov 15:S1097-2765(24)00877-3. doi: 10.1016/j.molcel.2024.10.037. Online ahead of print. Mol Cell. 2024. PMID: 39571580

2

Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay.

Gassaway BM, Huttlin EL, Huntsman EM, Yaron-Barir TM, Johnson JL, Kurmi K, Cantley LC, Paulo JA, Ringel AE, Gygi SP, Haigis MC. Gassaway BM, et al. Among authors: kurmi k. Mol Cell Proteomics. 2024 Jul;23(7):100801. doi: 10.1016/j.mcpro.2024.100801. Epub 2024 Jun 15. Mol Cell Proteomics. 2024. PMID: 38880243 Free PMC article.

3

Metabolic modulation of mitochondrial mass during CD4⁺ T cell activation.

Kurmi K, Liang D, van de Ven R, Georgiev P, Gassaway BM, Han S, Notarangelo G, Harris IS, Yao CH, Park JS, Hu SH, Peng J, Drijvers JM, Boswell S, Sokolov A, Dougan SK, Sorger PK, Gygi SP, Sharpe AH, Haigis MC. Kurmi K, et al. Cell Chem Biol. 2023 Sep 21;30(9):1064-1075.e8. doi: 10.1016/j.chembiol.2023.08.008. Cell Chem Biol. 2023. PMID: 37716347 Free PMC article.

4

Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis.

Yao CH, Park JS, Kurmi K, Hu SH, Notarangelo G, Crowley J, Jacobson H, Hui S, Sharpe AH, Haigis MC. Yao CH, et al. Among authors: kurmi k. Mol Cell. 2023 Apr 20;83(8):1340-1349.e7. doi: 10.1016/j.molcel.2023.03.023. Mol Cell. 2023. PMID: 37084714 Free PMC article.

5

Oncometabolite d-2HG alters T cell metabolism to impair CD8⁺ T cell function.

Notarangelo G, Spinelli JB, Perez EM, Baker GJ, Kurmi K, Elia I, Stopka SA, Baquer G, Lin JR, Golby AJ, Joshi S, Baron HF, Drijvers JM, Georgiev P, Ringel AE, Zaganjor E, McBrayer SK, Sorger PK, Sharpe AH, Wucherpfennig KW, Santagata S, Agar NYR, Suvà ML, Haigis MC. Notarangelo G, et al. Among authors: kurmi k. Science. 2022 Sep 30;377(6614):1519-1529. doi: 10.1126/science.abj5104. Epub 2022 Sep 29. Science. 2022. PMID: 36173860 Free PMC article.

6

Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8⁺ T cells.

Elia I, Rowe JH, Johnson S, Joshi S, Notarangelo G, Kurmi K, Weiss S, Freeman GJ, Sharpe AH, Haigis MC. Elia I, et al. Among authors: kurmi k. Cell Metab. 2022 Aug 2;34(8):1137-1150.e6. doi: 10.1016/j.cmet.2022.06.008. Epub 2022 Jul 11. Cell Metab. 2022. PMID: 35820416 Free PMC article.

7

Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells.

Saha T, Dash C, Jayabalan R, Khiste S, Kulkarni A, Kurmi K, Mondal J, Majumder PK, Bardia A, Jang HL, Sengupta S. Saha T, et al. Among authors: kurmi k. Nat Nanotechnol. 2022 Jan;17(1):98-106. doi: 10.1038/s41565-021-01000-4. Epub 2021 Nov 18. Nat Nanotechnol. 2022. PMID: 34795441 Free PMC article.

8

Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect.

Wiese EK, Hitosugi S, Loa ST, Sreedhar A, Andres-Beck LG, Kurmi K, Pang YP, Karnitz LM, Gonsalves WI, Hitosugi T. Wiese EK, et al. Among authors: kurmi k. Nat Metab. 2021 Jul;3(7):954-968. doi: 10.1038/s42255-021-00424-5. Epub 2021 Jul 5. Nat Metab. 2021. PMID: 34226744 Free PMC article.

9

Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8⁺ T Cells.

Drijvers JM, Gillis JE, Muijlwijk T, Nguyen TH, Gaudiano EF, Harris IS, LaFleur MW, Ringel AE, Yao CH, Kurmi K, Juneja VR, Trombley JD, Haigis MC, Sharpe AH. Drijvers JM, et al. Among authors: kurmi k. Cancer Immunol Res. 2021 Feb;9(2):184-199. doi: 10.1158/2326-6066.CIR-20-0384. Epub 2020 Dec 4. Cancer Immunol Res. 2021. PMID: 33277233 Free PMC article.

10

Nitrogen Metabolism in Cancer and Immunity.

Kurmi K, Haigis MC. Kurmi K, et al. Trends Cell Biol. 2020 May;30(5):408-424. doi: 10.1016/j.tcb.2020.02.005. Epub 2020 Mar 10. Trends Cell Biol. 2020. PMID: 32302552 Free PMC article. Review.

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