Upton HE - Search Results

1

Improved precision, sensitivity, and adaptability of Ordered Two-Template Relay cDNA library preparation for RNA sequencing.

Ferguson L, Upton HE, Pimentel SC, Jeans C, Ingolia NT, Collins K. Ferguson L, et al. Among authors: upton he. bioRxiv [Preprint]. 2024 Nov 10:2024.11.09.622813. doi: 10.1101/2024.11.09.622813. bioRxiv. 2024. PMID: 39574714 Free PMC article. Preprint.

2

Gammaherpesvirus infection triggers the formation of tRNA fragments from premature tRNAs.

Manning AC, Bashir MM, Jimenez AR, Upton HE, Collins K, Lowe TM, Tucker JM. Manning AC, et al. Among authors: upton he. bioRxiv [Preprint]. 2024 May 2:2024.05.01.592122. doi: 10.1101/2024.05.01.592122. bioRxiv. 2024. PMID: 38746336 Free PMC article. Preprint.

3

Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage.

Manning AC, Bashir MM, Jimenez AR, Upton HE, Collins K, Lowe TM, Tucker JM. Manning AC, et al. Among authors: upton he. bioRxiv [Preprint]. 2024 Feb 17:2024.02.16.580780. doi: 10.1101/2024.02.16.580780. bioRxiv. 2024. PMID: 38405876 Free PMC article. Preprint.

4

Streamlined and sensitive mono- and di-ribosome profiling in yeast and human cells.

Ferguson L, Upton HE, Pimentel SC, Mok A, Lareau LF, Collins K, Ingolia NT. Ferguson L, et al. Among authors: upton he. Nat Methods. 2023 Nov;20(11):1704-1715. doi: 10.1038/s41592-023-02028-1. Epub 2023 Oct 2. Nat Methods. 2023. PMID: 37783882 Free PMC article.

5

Nanopore molecular trajectories of a eukaryotic reverse transcriptase reveal a long-range RNA structure sensing mechanism.

Shaw A, Craig JM, Amiri H, Kim J, Upton HE, Pimentel SC, Huang JR, Marqusee S, Collins K, Gundlach JH, Bustamante CJ. Shaw A, et al. Among authors: upton he. bioRxiv [Preprint]. 2023 Nov 1:2023.04.05.535757. doi: 10.1101/2023.04.05.535757. bioRxiv. 2023. PMID: 37066208 Free PMC article. Preprint.

6

Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase.

Pimentel SC, Upton HE, Collins K. Pimentel SC, et al. Among authors: upton he. J Biol Chem. 2022 Mar;298(3):101624. doi: 10.1016/j.jbc.2022.101624. Epub 2022 Jan 21. J Biol Chem. 2022. PMID: 35065960 Free PMC article.

7

Low-bias ncRNA libraries using ordered two-template relay: Serial template jumping by a modified retroelement reverse transcriptase.

Upton HE, Ferguson L, Temoche-Diaz MM, Liu XM, Pimentel SC, Ingolia NT, Schekman R, Collins K. Upton HE, et al. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2107900118. doi: 10.1073/pnas.2107900118. Proc Natl Acad Sci U S A. 2021. PMID: 34649994 Free PMC article.

8

Telomerase Mechanism of Telomere Synthesis.

Wu RA, Upton HE, Vogan JM, Collins K. Wu RA, et al. Among authors: upton he. Annu Rev Biochem. 2017 Jun 20;86:439-460. doi: 10.1146/annurev-biochem-061516-045019. Epub 2017 Jan 30. Annu Rev Biochem. 2017. PMID: 28141967 Free PMC article. Review.

9

Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes.

Upton HE, Chan H, Feigon J, Collins K. Upton HE, et al. J Biol Chem. 2017 Jan 6;292(1):217-228. doi: 10.1074/jbc.M116.763664. Epub 2016 Nov 28. J Biol Chem. 2017. PMID: 27895115 Free PMC article.

10

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.

Jiang J, Chan H, Cash DD, Miracco EJ, Ogorzalek Loo RR, Upton HE, Cascio D, O'Brien Johnson R, Collins K, Loo JA, Zhou ZH, Feigon J. Jiang J, et al. Among authors: upton he. Science. 2015 Oct 30;350(6260):aab4070. doi: 10.1126/science.aab4070. Epub 2015 Oct 15. Science. 2015. PMID: 26472759 Free PMC article.

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