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Use of Affimer Technology for Inhibition of α2-antiplasmin and Enhancement of Fibrinolysis.
Pechlivani N, Alsayejh B, Almutairi MK, Simmons K, Gaule T, Phoenix F, Kietsiriroje N, Ponnambalam S, Duval C, Ariëns RAS, Tiede C, Tomlinson DC, Ajjan R. Pechlivani N, et al. Among authors: ponnambalam s. Blood Adv. 2024 Nov 6:bloodadvances.2024014235. doi: 10.1182/bloodadvances.2024014235. Online ahead of print. Blood Adv. 2024. PMID: 39504559 Free article.
"Affimer" synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation.
Roper BWR, Tiede C, Abdul-Zani I, Cuthbert GA, Jade D, Al-Aufi A, Critchley WR, Saikia Q, Homer-Vanniasinkam S, Sawamura T, McPherson MJ, Harrison MA, Tomlinson DC, Ponnambalam S. Roper BWR, et al. Among authors: ponnambalam s. J Biol Chem. 2023 Nov;299(11):105325. doi: 10.1016/j.jbc.2023.105325. Epub 2023 Oct 5. J Biol Chem. 2023. PMID: 37805141 Free PMC article.
VEGFR endocytosis: Implications for angiogenesis.
Saikia Q, Reeve H, Alzahrani A, Critchley WR, Zeqiraj E, Divan A, Harrison MA, Ponnambalam S. Saikia Q, et al. Among authors: ponnambalam s. Prog Mol Biol Transl Sci. 2023;194:109-139. doi: 10.1016/bs.pmbts.2022.06.021. Epub 2022 Jul 15. Prog Mol Biol Transl Sci. 2023. PMID: 36631189
132 results