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Phase Ib pharmacodynamic study of the MNK inhibitor Tomivosertib (eFT508) combined with paclitaxel in patients with refractory metastatic breast cancer.
Ferrario C, Mackey J, Gelmon KA, Levasseur N, Sorensen PH, Oo HZ, Negri GL, Tse VWL, Spencer SE, Cheng G, Morin GB, Del Rincon S, Cotechini T, Gonçalves C, Hindmarch CCT, Miller WH, Amiri M, Basiri T, Villareal-Corpuz V, Sperry S, Gregorczyk K, Spera G, Sonenberg N, Pollak M. Ferrario C, et al. Among authors: negri gl. Clin Cancer Res. 2024 Nov 22. doi: 10.1158/1078-0432.CCR-24-0841. Online ahead of print. Clin Cancer Res. 2024. PMID: 39576211
Changes in the tumour microenvironment mark the transition from serous borderline tumour to low-grade serous carcinoma.
Vallejos R, Zhantuyakova A, Negri GL, Martin SD, Spencer SE, Thornton S, Leung S, Lynch B, Qin Y, Chow C, Liang B, Zdravko S, Douglas JM, Milne K, Mateyko B, Nelson BH, Howitt BE, Kommoss FK, Horn LC, Hoang L, Singh N, Morin GB, Huntsman DG, Cochrane D. Vallejos R, et al. Among authors: negri gl. J Pathol. 2024 Oct;264(2):197-211. doi: 10.1002/path.6338. Epub 2024 Jul 31. J Pathol. 2024. PMID: 39081243
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Li L, Verma SP, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, John CM, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Mortenson KL, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: negri gl. Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5. Nat Commun. 2024. PMID: 38326311 Free PMC article.
Dependence of human cell survival and proliferation on the CASP3 prodomain.
Eskandari E, Negri GL, Tan S, MacAldaz ME, Ding S, Long J, Nielsen K, Spencer SE, Morin GB, Eaves CJ. Eskandari E, et al. Among authors: negri gl. Cell Death Discov. 2024 Feb 6;10(1):63. doi: 10.1038/s41420-024-01826-6. Cell Death Discov. 2024. PMID: 38321033 Free PMC article.
Characterizing the secretome of EGFR mutant lung adenocarcinoma.
Luu JK, Johnson FD, Jajarmi J, Sihota T, Shi R, Lu D, Farnsworth D, Spencer SE, Negri GL, Morin GB, Lockwood WW. Luu JK, et al. Among authors: negri gl. Front Oncol. 2024 Jan 8;13:1286821. doi: 10.3389/fonc.2023.1286821. eCollection 2023. Front Oncol. 2024. PMID: 38260835 Free PMC article.
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97.
Pozner A, Verma SP, Li L, Wang S, Barrott JJ, Nelson ML, Yu JSE, Negri GL, Colborne S, Hughes CS, Zhu JF, Lambert SL, Carroll LS, Smith-Fry K, Stewart MG, Kannan S, Jensen B, Mortenson KL, John C, Sikdar S, Liu H, Dang NH, Bourdage J, Li J, Vahrenkamp JM, Groundland JS, Wustrack R, Senger DL, Zemp FJ, Mahoney DJ, Gertz J, Zhang X, Lazar AJ, Hirst M, Morin GB, Nielsen TO, Shen PS, Jones KB. Pozner A, et al. Among authors: negri gl. bioRxiv [Preprint]. 2023 Oct 2:2023.09.29.560242. doi: 10.1101/2023.09.29.560242. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 7;15(1):1165. doi: 10.1038/s41467-024-45280-5. PMID: 37873234 Free PMC article. Updated. Preprint.
Surface and Global Proteome Analyses Identify ENPP1 and Other Surface Proteins as Actionable Immunotherapeutic Targets in Ewing Sarcoma.
Mooney B, Negri GL, Shyp T, Delaidelli A, Zhang HF, Spencer Miko SE, Weiner AK, Radaoui AB, Shraim R, Lizardo MM, Hughes CS, Li A, El-Naggar AM, Rouleau M, Li W, Dimitrov DS, Kurmasheva RT, Houghton PJ, Diskin SJ, Maris JM, Morin GB, Sorensen PH. Mooney B, et al. Among authors: negri gl. Clin Cancer Res. 2024 Mar 1;30(5):1022-1037. doi: 10.1158/1078-0432.CCR-23-2187. Clin Cancer Res. 2024. PMID: 37812652 Free PMC article.
66 results