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An orally available Mpro/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo.
Chu H, Shuai H, Qiao J, Yoon C, Zhang G, Hou Y, Xia X, Wang L, Deng X, Wang Y, Li Q, Du L, Liu Y, Zhou M, Wong HT, Liu H, Hu B, Chen Y, Fang Z, Xia Z, Chai Y, Shi J, Wang Y, Zhu T, Zhang H, Yuan S, Zhou J, Chan J, Yuen KY, Xu C, Lei J, Yang S. Chu H, et al. Among authors: fang z. Res Sq [Preprint]. 2024 Nov 21:rs.3.rs-5454588. doi: 10.21203/rs.3.rs-5454588/v1. Res Sq. 2024. PMID: 39606435 Free PMC article. Preprint.
DNA-guided CRISPR/Cas12 for RNA targeting.
Orosco C, Rananaware SR, Huang B, Hanna MP, Ahmadimashhadi MR, Lewis JG, Baugh MP, Bodin AP, Flannery SJ, Lange IH, Fang ZR, Karalkar VN, Meister KS, Jain PK. Orosco C, et al. Among authors: fang zr. medRxiv [Preprint]. 2024 Nov 22:2024.11.21.24317744. doi: 10.1101/2024.11.21.24317744. medRxiv. 2024. PMID: 39606390 Free PMC article. Preprint.
7,805 results