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110 results

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Page 1
Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.
Sun S, You E, Hong J, Hoyos D, Del Priore IS, Tsanov KM, Mattagajasingh O, Di Gioacchino A, Marhon SA, Chacon-Barahona J, Li H, Jiang H, Hozeifi S, Rosas-Bringas O, Xu KH, Song Y, Lang ER, Rojas AS, Nieman LT, Patel BK, Murali R, Chanda P, Karacay A, Vabret N, De Carvalho DD, Zenklusen D, LaCava J, Lowe SW, Ting DT, Iacobuzio-Donahue CA, Solovyov A, Greenbaum BD. Sun S, et al. Among authors: de carvalho dd. Immunity. 2024 Nov 20:S1074-7613(24)00494-1. doi: 10.1016/j.immuni.2024.10.015. Online ahead of print. Immunity. 2024. PMID: 39577413
Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.
Feng S, Marhon SA, Sokolowski DJ, D'Costa A, Soares F, Mehdipour P, Ishak C, Loo Yau H, Ettayebi I, Patel PS, Chen R, Liu J, Zuzarte PC, Ho KC, Ho B, Ning S, Huang A, Arrowsmith CH, Wilson MD, Simpson JT, De Carvalho DD. Feng S, et al. Among authors: de carvalho dd. Nat Commun. 2024 Oct 29;15(1):9321. doi: 10.1038/s41467-024-53515-8. Nat Commun. 2024. PMID: 39472584 Free PMC article.
Clinical validation of a tissue-agnostic genome-wide methylome enrichment molecular residual disease assay for head and neck malignancies.
Liu G, Huang SH, Ailles L, Rey-McIntyre K, Melton CA, Shen SY, Burgener JM, Brown B, Zhang J, Min J, Wang Y, Hall O, Jones JT, Budhraja K, Provance JB, Sosa EV, Licon A, Williams A, Bratman SV, Allen BA, Zhang J, Hartman AR, De Carvalho DD. Liu G, et al. Among authors: de carvalho dd. Ann Oncol. 2024 Sep 14:S0923-7534(24)03929-2. doi: 10.1016/j.annonc.2024.08.2348. Online ahead of print. Ann Oncol. 2024. PMID: 39389887 Free article.
In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.
Su P, Liu Y, Chen T, Xue Y, Zeng Y, Zhu G, Chen S, Teng M, Ci X, Guo M, He MY, Hao J, Chu V, Xu W, Wang S, Mehdipour P, Xu X, Marhon SA, Soares F, Pham NA, Wu BX, Her PH, Feng S, Alshamlan N, Khalil M, Krishnan R, Yu F, Chen C, Burrows F, Hakem R, Lupien M, Harding S, Lok BH, O'Brien C, Berlin A, De Carvalho DD, Brooks DG, Schramek D, Tsao MS, He HH. Su P, et al. Among authors: de carvalho dd. Nat Genet. 2024 Sep;56(9):1890-1902. doi: 10.1038/s41588-024-01874-9. Epub 2024 Sep 3. Nat Genet. 2024. PMID: 39227744 Free PMC article.
Use of Machine Perfusion to Increase the Number of Expanded Criteria Deceased Donor Kidney Transplants: A Pharmacoeconomic Analysis.
Tedesco Silva H Jr, Ramos TRM, de Carvalho DBM, Ferreira GF, de Andrade JMM, de Andrade LGM, Abbud-Filho M, Foresto RD, Manfro RC, Esmeraldo RM, Freitas TVS, Garcia VD, Pestana JM, Fonseca MCM. Tedesco Silva H Jr, et al. Transplant Direct. 2024 Jul 5;10(8):e1668. doi: 10.1097/TXD.0000000000001668. eCollection 2024 Aug. Transplant Direct. 2024. PMID: 38988688 Free PMC article.
Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer.
Hosseini A, Lindholm HT, Chen R, Mehdipour P, Marhon SA, Ishak CA, Moore PC, Classon M, Di Gioacchino A, Greenbaum B, De Carvalho DD. Hosseini A, et al. Among authors: de carvalho dd. Cell Rep. 2024 Feb 27;43(2):113684. doi: 10.1016/j.celrep.2024.113684. Epub 2024 Jan 22. Cell Rep. 2024. PMID: 38261511 Free article.
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet.
Viner C, Ishak CA, Johnson J, Walker NJ, Shi H, Sjöberg-Herrera MK, Shen SY, Lardo SM, Adams DJ, Ferguson-Smith AC, De Carvalho DD, Hainer SJ, Bailey TL, Hoffman MM. Viner C, et al. Among authors: de carvalho dd. Genome Biol. 2024 Jan 8;25(1):11. doi: 10.1186/s13059-023-03070-0. Genome Biol. 2024. PMID: 38191487 Free PMC article.
Proceedings of the inaugural Dark Genome Symposium: November 2022.
Boeke JD, Burns KH, Chiappinelli KB, Classon M, Coffin JM, DeCarvalho DD, Dukes JD, Greenbaum B, Kassiotis G, Knutson SK, Levine AJ, Nath A, Papa S, Rios D, Sedivy J, Ting DT. Boeke JD, et al. Mob DNA. 2023 Nov 21;14(1):18. doi: 10.1186/s13100-023-00306-5. Mob DNA. 2023. PMID: 37990347 Free PMC article.
Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia.
de Castro FA, Mehdipour P, Chakravarthy A, Ettayebi I, Loo Yau H, Medina TS, Marhon SA, de Almeida FC, Bianco TM, Arruda AGF, Devlin R, de Figueiredo-Pontes LL, Chahud F, da Costa Cacemiro M, Minden MD, Gupta V, De Carvalho DD. de Castro FA, et al. Among authors: de carvalho dd. Br J Haematol. 2024 Jan;204(1):206-220. doi: 10.1111/bjh.19107. Epub 2023 Sep 19. Br J Haematol. 2024. PMID: 37726227
110 results