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Page 1
Seratrodast inhibits ferroptosis by suppressing lipid peroxidation.
Tschuck J, Tonnus W, Gavali S, Kolak A, Mallais M, Maremonti F, Sato M, Rothenaigner I, Friedmann Angeli JP, Pratt DA, Linkermann A, Hadian K. Tschuck J, et al. Among authors: friedmann angeli jp. Cell Death Dis. 2024 Nov 22;15(11):853. doi: 10.1038/s41419-024-07251-y. Cell Death Dis. 2024. PMID: 39578434 Free PMC article.
PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance.
Chen Z, Inague A, Kaushal K, Fazeli G, Schilling D, Xavier da Silva TN, Dos Santos AF, Cheytan T, Freitas FP, Yildiz U, Viviani LG, Lima RS, Pinz MP, Medeiros I, Iijima TS, Alegria TGP, Pereira da Silva R, Diniz LR, Weinzweig S, Klein-Seetharaman J, Trumpp A, Mañas A, Hondal R, Bartenhagen C, Fischer M, Shimada BK, Seale LA, Chillon TS, Fabiano M, Schomburg L, Schweizer U, Netto LE, Meotti FC, Dick TP, Alborzinia H, Miyamoto S, Friedmann Angeli JP. Chen Z, et al. Among authors: friedmann angeli jp. Mol Cell. 2024 Nov 7:S1097-2765(24)00867-0. doi: 10.1016/j.molcel.2024.10.027. Online ahead of print. Mol Cell. 2024. PMID: 39547224 Free article.
Iron: The Secret Ingredient Breaking PARPi Resistance.
Alborzinia H, Friedmann Angeli JP. Alborzinia H, et al. Among authors: friedmann angeli jp. Cancer Discov. 2024 Aug 2;14(8):1372-1374. doi: 10.1158/2159-8290.CD-24-0775. Cancer Discov. 2024. PMID: 39091202
Ferroptosis in health and disease.
Berndt C, Alborzinia H, Amen VS, Ayton S, Barayeu U, Bartelt A, Bayir H, Bebber CM, Birsoy K, Böttcher JP, Brabletz S, Brabletz T, Brown AR, Brüne B, Bulli G, Bruneau A, Chen Q, DeNicola GM, Dick TP, Distéfano A, Dixon SJ, Engler JB, Esser-von Bieren J, Fedorova M, Friedmann Angeli JP, Friese MA, Fuhrmann DC, García-Sáez AJ, Garbowicz K, Götz M, Gu W, Hammerich L, Hassannia B, Jiang X, Jeridi A, Kang YP, Kagan VE, Konrad DB, Kotschi S, Lei P, Le Tertre M, Lev S, Liang D, Linkermann A, Lohr C, Lorenz S, Luedde T, Methner A, Michalke B, Milton AV, Min J, Mishima E, Müller S, Motohashi H, Muckenthaler MU, Murakami S, Olzmann JA, Pagnussat G, Pan Z, Papagiannakopoulos T, Pedrera Puentes L, Pratt DA, Proneth B, Ramsauer L, Rodriguez R, Saito Y, Schmidt F, Schmitt C, Schulze A, Schwab A, Schwantes A, Soula M, Spitzlberger B, Stockwell BR, Thewes L, Thorn-Seshold O, Toyokuni S, Tonnus W, Trumpp A, Vandenabeele P, Vanden Berghe T, Venkataramani V, Vogel FCE, von Karstedt S, Wang F, Westermann F, Wientjens C, Wilhelm C, Wölk M, Wu K, Yang X, Yu F, Zou Y, Conrad M. Berndt C, et al. Among authors: friedmann angeli jp. Redox Biol. 2024 Sep;75:103211. doi: 10.1016/j.redox.2024.103211. Epub 2024 May 30. Redox Biol. 2024. PMID: 38908072 Free PMC article. Review.
PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance.
Chen Z, Inague A, Kaushal K, Fazeli G, N Xavier da Silva T, Ferreira Dos Santos A, Cheytan T, Porto Freitas F, Yildiz U, Gasparello Viviani L, Santiago Lima R, Peglow Pinz M, Medeiros I, Geronimo Pires Alegria T, Pereira da Silva R, Regina Diniz L, Weinzweig S, Klein-Seetharaman J, Trumpp A, Manas A, Hondal R, Fischer M, Bartenhagen C, Shimada BK, Seale LA, Fabiano M, Schweizer U, Netto LE, Meotti FC, Alborzinia H, Miyamoto S, Friedmann Angeli JP. Chen Z, et al. Among authors: friedmann angeli jp. bioRxiv [Preprint]. 2024 Jun 6:2024.06.04.597364. doi: 10.1101/2024.06.04.597364. bioRxiv. 2024. Update in: Mol Cell. 2024 Nov 7:S1097-2765(24)00867-0. doi: 10.1016/j.molcel.2024.10.027 PMID: 38895225 Free PMC article. Updated. Preprint.
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.
Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Freitas FP, et al. Among authors: friedmann angeli jp. Nature. 2024 Feb;626(7998):401-410. doi: 10.1038/s41586-023-06878-9. Epub 2024 Jan 31. Nature. 2024. PMID: 38297129
Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent manner.
Meinert M, Jessen C, Hufnagel A, Kreß JKC, Burnworth M, Däubler T, Gallasch T, Xavier da Silva TN, Dos Santos AF, Ade CP, Schmitz W, Kneitz S, Friedmann Angeli JP, Meierjohann S. Meinert M, et al. Among authors: friedmann angeli jp. Redox Biol. 2024 Apr;70:103011. doi: 10.1016/j.redox.2023.103011. Epub 2023 Dec 27. Redox Biol. 2024. PMID: 38219574 Free PMC article.
37 results