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PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity.
De Siqueira MK, Li G, Zhao Y, Wang S, Ahn IS, Tamboline M, Hildreth AD, Larios J, Schcolnik-Cabrera A, Nouhi Z, Zhang Z, Tol MJ, Pandey V, Xu S, O'Sullivan TE, Mack JJ, Tontonoz P, Sallam T, Wohlschlegel JA, Hulea L, Xiao X, Yang X, Villanueva CJ. De Siqueira MK, et al. Among authors: villanueva cj. Cell Rep. 2024 Nov 7:114945. doi: 10.1016/j.celrep.2024.114945. Online ahead of print. Cell Rep. 2024. PMID: 39579770 Free article.
Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors.
Patel S, Ganbold K, Cho CH, Siddiqui J, Yildiz R, Sparman N, Sadeh S, Nguyen CM, Wang J, Whitelegge JP, Fried SK, Waki H, Villanueva CJ, Seldin MM, Sakaguchi S, Ellmeier W, Tontonoz P, Rajbhandari P. Patel S, et al. Among authors: villanueva cj. Nat Commun. 2024 Oct 2;15(1):8533. doi: 10.1038/s41467-024-52917-y. Nat Commun. 2024. PMID: 39358382 Free PMC article.
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis.
Johnson JM, Peterlin AD, Balderas E, Sustarsic EG, Maschek JA, Lang MJ, Jara-Ramos A, Panic V, Morgan JT, Villanueva CJ, Sanchez A, Rutter J, Lodhi IJ, Cox JE, Fisher-Wellman KH, Chaudhuri D, Gerhart-Hines Z, Funai K. Johnson JM, et al. Among authors: villanueva cj. Sci Adv. 2023 Feb 24;9(8):eade7864. doi: 10.1126/sciadv.ade7864. Epub 2023 Feb 24. Sci Adv. 2023. PMID: 36827367 Free PMC article.
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis.
Xiao X, Kennelly JP, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P. Xiao X, et al. Among authors: villanueva cj. Nat Metab. 2023 Jan;5(1):165-181. doi: 10.1038/s42255-022-00722-6. Epub 2023 Jan 16. Nat Metab. 2023. PMID: 36646756 Free PMC article.
Adipose-tissue plasticity in health and disease.
Sakers A, De Siqueira MK, Seale P, Villanueva CJ. Sakers A, et al. Among authors: villanueva cj. Cell. 2022 Feb 3;185(3):419-446. doi: 10.1016/j.cell.2021.12.016. Cell. 2022. PMID: 35120662 Free PMC article. Review.
When fat talks, the gut listens: IRONing out metabolism.
De Siqueira MK, Villanueva CJ. De Siqueira MK, et al. Among authors: villanueva cj. Cell Metab. 2021 Aug 3;33(8):1505-1506. doi: 10.1016/j.cmet.2021.07.012. Cell Metab. 2021. PMID: 34348093 Free article.
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis.
Panic V, Pearson S, Banks J, Tippetts TS, Velasco-Silva JN, Lee S, Simcox J, Geoghegan G, Bensard CL, van Ry T, Holland WL, Summers SA, Cox J, Ducker GS, Rutter J, Villanueva CJ. Panic V, et al. Among authors: villanueva cj. Elife. 2020 Aug 14;9:e52558. doi: 10.7554/eLife.52558. Elife. 2020. PMID: 32795388 Free PMC article.
38 results