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Page 1
Switching Residues: A Platform for the Synthesis of Fidaxomicin Antibiotics.
Jung E, Griesser T, Costafrolaz J, Duverger O, Mattenberger Y, Dittmann S, Dorst A, Major A, Dailler D, Schäfle D, Sievers S, Brodolin K, Viollier PH, Sander P, Gademann K. Jung E, et al. Among authors: sievers s. Angew Chem Int Ed Engl. 2024 Nov 25:e202419095. doi: 10.1002/anie.202419095. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39584779
Magnetic force microscopy: High quality-factor two-pass mode.
Habenschaden C, Sievers S, Klasen A, Cerreta A, Schumacher HW. Habenschaden C, et al. Among authors: sievers s. Rev Sci Instrum. 2024 Nov 1;95(11):113704. doi: 10.1063/5.0226633. Rev Sci Instrum. 2024. PMID: 39530792
Distribution and diversity of classical deacylases in bacteria.
Graf LG, Moreno-Yruela C, Qin C, Schulze S, Palm GJ, Schmöker O, Wang N, Hocking DM, Jebeli L, Girbardt B, Berndt L, Dörre B, Weis DM, Janetzky M, Albrecht D, Zühlke D, Sievers S, Strugnell RA, Olsen CA, Hofmann K, Lammers M. Graf LG, et al. Among authors: sievers s. Nat Commun. 2024 Nov 3;15(1):9496. doi: 10.1038/s41467-024-53903-0. Nat Commun. 2024. PMID: 39489725 Free PMC article.
Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3.
Hennes E, Lucas B, Scholes NS, Cheng XF, Scott DC, Bischoff M, Reich K, Gasper R, Lucas M, Xu TT, Pulvermacher LM, Dötsch L, Imrichova H, Brause A, Naredla KR, Sievers S, Kumar K, Janning P, Gersch M, Murray PJ, Schulman BA, Winter GE, Ziegler S, Waldmann H. Hennes E, et al. Among authors: sievers s. bioRxiv [Preprint]. 2024 Jul 13:2024.07.10.602857. doi: 10.1101/2024.07.10.602857. bioRxiv. 2024. PMID: 39026748 Free PMC article. Preprint.
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP.
Cigler M, Imrichova H, Frommelt F, Caramelle L, Depta L, Rukavina A, Kagiou C, Hannich JT, Mayor-Ruiz C, Superti-Furga G, Sievers S, Forrester A, Laraia L, Waldmann H, Winter GE. Cigler M, et al. Among authors: sievers s. Nat Chem Biol. 2024 Jun 21. doi: 10.1038/s41589-024-01614-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38907113
The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2.
Patil S, Cremosnik G, Dötsch L, Flegel J, Schulte B, Maier KC, Žumer K, Cramer P, Janning P, Sievers S, Ziegler S, Waldmann H. Patil S, et al. Among authors: sievers s. Angew Chem Int Ed Engl. 2024 Aug 5;63(32):e202404645. doi: 10.1002/anie.202404645. Epub 2024 Jul 4. Angew Chem Int Ed Engl. 2024. PMID: 38801173
195 results