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Page 1
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Zein JG, Zounemat-Kerman N, Adcock IM, Hu B, Attaway A, Castro M, Dahlén SE, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore W, Peters MC, Sumino K, Townsend E, Woodruff P, Ortega VE, Wenzel SE, Meyers DA, Chung KF, Bleecker ER; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III). Zein JG, et al. Among authors: wenzel se. Lancet Respir Med. 2024 Nov 22:S2213-2600(24)00250-9. doi: 10.1016/S2213-2600(24)00250-9. Online ahead of print. Lancet Respir Med. 2024. PMID: 39586307
Ferroptosis of select skin epithelial cells initiates and maintains chronic systemic immune-mediated psoriatic disease.
Vats K, Tian H, Singh K, Tyurina YY, Sparvero LJ, Tyurin VA, Kruglov O, Chang A, Wang J, Green F, Samovich SN, Zhang J, Chattopadhyay A, Murray N, Shah VK, Mathers AR, Chandran UR, Pilewski JM, Kellum JA, Wenzel SE, Bayir H, Kagan VE, Bunimovich YL. Vats K, et al. Among authors: wenzel se. J Clin Invest. 2024 Nov 21:e183219. doi: 10.1172/JCI183219. Online ahead of print. J Clin Invest. 2024. PMID: 39570671 Free article.
Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations.
Xu W, Hong YS, Hu B, Comhair SAA, Janocha AJ, Zein JG, Chen R, Meyers DA, Mauger DT, Ortega VE, Bleecker ER, Castro M, Denlinger LC, Fahy JV, Israel E, Levy BD, Jarjour NN, Moore WC, Wenzel SE, Gaston B, Liu C, Arking DE, Erzurum SC; National Heart, Lung, and Blood Institute (NHLBI) Severe Asthma Research Program and TOPMed mtDNA Working Group in NHLBI Trans-omics for Precision Medicine (TOPMed) Consortium. Xu W, et al. Among authors: wenzel se. J Allergy Clin Immunol. 2024 Sep 3:S0091-6749(24)00906-0. doi: 10.1016/j.jaci.2024.08.022. Online ahead of print. J Allergy Clin Immunol. 2024. PMID: 39237012
Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents.
Park SY, Fowler S, Shaw DE, Adcock IM, Sousa AR, Djukanovic R, Dahlen SE, Sterk PJ, Kermani NZ, Calhoun W, Israel E, Castro M, Mauger D, Meyers D, Bleecker E, Moore W, Busse W, Jarjour N, Denlinger L, Levy B, Choi BH, Kim SH, Jang AS, Lee T, Cho YJ, Shin YS, Cho SH, Won S, Cruz AA, Wenzel SE, Chung KF, Kim TB. Park SY, et al. Among authors: wenzel se. Allergy Asthma Immunol Res. 2024 Jul;16(4):338-352. doi: 10.4168/aair.2024.16.4.338. Allergy Asthma Immunol Res. 2024. PMID: 39155735 Free PMC article.
Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes.
Yamada K, St Croix C, Stolz DB, Tyurina YY, Tyurin VA, Bradley LR, Kapralov AA, Deng Y, Zhou X, Wei Q, Liao B, Fukuda N, Sullivan M, Trudeau J, Ray A, Kagan VE, Zhao J, Wenzel SE. Yamada K, et al. Among authors: wenzel se. Nat Commun. 2024 Jul 10;15(1):5818. doi: 10.1038/s41467-024-50222-2. Nat Commun. 2024. PMID: 38987265 Free PMC article.
Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor.
Boomer J, Choi J, Alsup A, McGregor MC, Lieu J, Johnson C, Hall C, Shi X, Kim T, Goss C, Lew D, Christenson S, Woodruff PG, Hastie A, Mauger D, Wenzel SE, Hoffman EA, Schechtman KB, Castro M. Boomer J, et al. Among authors: wenzel se. Am J Respir Crit Care Med. 2024 Jun 27. doi: 10.1164/rccm.202307-1266OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38935626
Peroxidase-mediated mucin cross-linking drives pathologic mucus gel formation in IL-13-stimulated airway epithelial cells.
Liegeois MA, Braunreuther M, Charbit AR, Raymond WW, Tang M, Woodruff PG, Christenson SA, Castro M, Erzurum SC, Israel E, Jarjour NN, Levy BD, Moore WC, Wenzel SE, Fuller GG, Fahy JV. Liegeois MA, et al. Among authors: wenzel se. JCI Insight. 2024 Jun 18;9(15):e181024. doi: 10.1172/jci.insight.181024. JCI Insight. 2024. PMID: 38889046 Free PMC article.
370 results