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Page 1
A deconvolution framework that uses single-cell sequencing plus a small benchmark dataset for accurate analysis of cell type ratios in complex tissue samples.
Guo S, Liu X, Cheng X, Jiang Y, Ji S, Liang Q, Koval A, Li Y, Owen LA, Kim IK, Aparicio A, Lee S, Sood AK, Kopetz S, Shen JP, Weinstein JN, DeAngelis MM, Chen R, Wang W. Guo S, et al. Among authors: owen la. Genome Res. 2024 Nov 25:gr.278822.123. doi: 10.1101/gr.278822.123. Online ahead of print. Genome Res. 2024. PMID: 39586714 Free article.
Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling.
Wu B, Bennett HM, Ye X, Sridhar A, Eidenschenk C, Everett C, Nazarova EV, Chen HH, Kim IK, Deangelis M, Owen LA, Chen C, Lau J, Shi M, Lund JM, Xavier-Magalhães A, Patel N, Liang Y, Modrusan Z, Darmanis S. Wu B, et al. Among authors: owen la. Nat Commun. 2024 Oct 23;15(1):9146. doi: 10.1038/s41467-024-53227-z. Nat Commun. 2024. PMID: 39443484 Free PMC article.
Genome-wide association identifies novel ROP risk loci in a multiethnic cohort.
Li X, Owen LA, Taylor KD, Ostmo S, Chen YI, Coyner AS, Sonmez K, Hartnett ME, Guo X, Ipp E, Roll K, Genter P, Chan RVP, DeAngelis MM, Chiang MF, Campbell JP, Rotter JI; i-ROP Consortium. Li X, et al. Among authors: owen la. Commun Biol. 2024 Jan 17;7(1):107. doi: 10.1038/s42003-023-05743-9. Commun Biol. 2024. PMID: 38233474 Free PMC article.
Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration.
Shwani T, Zhang C, Owen LA, Shakoor A, Vitale AT, Lillvis JH, Barr JL, Cromwell P, Finley R, Husami N, Au E, Zavala RA, Graves EC, Zhang SX, Farkas MH, Ammar DA, Allison KM, Tawfik A, Sherva RM, Li M, Stambolian D, Kim IK, Farrer LA, DeAngelis MM. Shwani T, et al. Among authors: owen la. Cells. 2023 Nov 21;12(23):2668. doi: 10.3390/cells12232668. Cells. 2023. PMID: 38067097 Free PMC article.
Integrated multi-omics single cell atlas of the human retina.
Li J, Wang J, Ibarra IL, Cheng X, Luecken MD, Lu J, Monavarfeshani A, Yan W, Zheng Y, Zuo Z, Colborn SLZ, Cortez BS, Owen LA, Tran NM, Shekhar K, Sanes JR, Stout JT, Chen S, Li Y, DeAngelis MM, Theis FJ, Chen R. Li J, et al. Among authors: owen la. Res Sq [Preprint]. 2023 Nov 17:rs.3.rs-3471275. doi: 10.21203/rs.3.rs-3471275/v1. Res Sq. 2023. PMID: 38014002 Free PMC article. Preprint.
DeMixSC: a deconvolution framework that uses single-cell sequencing plus a small benchmark dataset for improved analysis of cell-type ratios in complex tissue samples.
Guo S, Liu X, Cheng X, Jiang Y, Ji S, Liang Q, Koval A, Li Y, Owen LA, Kim IK, Aparicio A, Shen JP, Kopetz S, Weinstein JN, DeAngelis MM, Chen R, Wang W. Guo S, et al. Among authors: owen la. bioRxiv [Preprint]. 2023 Nov 11:2023.10.10.561733. doi: 10.1101/2023.10.10.561733. bioRxiv. 2023. PMID: 37873318 Free PMC article. Preprint.
A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration.
Orozco LD, Owen LA, Hofmann J, Stockwell AD, Tao J, Haller S, Mukundan VT, Clarke C, Lund J, Sridhar A, Mayba O, Barr JL, Zavala RA, Graves EC, Zhang C, Husami N, Finley R, Au E, Lillvis JH, Farkas MH, Shakoor A, Sherva R, Kim IK, Kaminker JS, Townsend MJ, Farrer LA, Yaspan BL, Chen HH, DeAngelis MM. Orozco LD, et al. Among authors: owen la. Cell Genom. 2023 Apr 18;3(6):100302. doi: 10.1016/j.xgen.2023.100302. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388919 Free PMC article.
Genome-wide association identifies novel ROP risk loci in a multi-ethnic cohort.
Rotter J, Li X, Owen LA, Taylor K, Ostmo S, Chen YI, Coyner A, Sonmez K, Hartnett ME, Guo X, Ipp E, Roll K, Genter P, Chan RVP, DeAngelis M, Chiang M, Campbell JP. Rotter J, et al. Among authors: owen la. Res Sq [Preprint]. 2023 May 16:rs.3.rs-2855404. doi: 10.21203/rs.3.rs-2855404/v1. Res Sq. 2023. Update in: Commun Biol. 2024 Jan 17;7(1):107. doi: 10.1038/s42003-023-05743-9 PMID: 37292936 Free PMC article. Updated. Preprint.
Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence.
Barr JL, Feehan M, Tak C, Owen LA, Finley RC, Cromwell PA, Lillvis JH, Hicks PM, Au E, Farkas MH, Weiner A, Reynolds AL, Sieminski SF, Sherva RM, Munger MA, Brilliant MH, DeAngelis MM. Barr JL, et al. Among authors: owen la. Int J Mol Sci. 2023 Mar 15;24(6):5636. doi: 10.3390/ijms24065636. Int J Mol Sci. 2023. PMID: 36982708 Free PMC article.
57 results