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Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Topper MJ, Guarnieri JW, Haltom JA, Chadburn A, Cope H, Frere J, An J, Borczuk A, Sinha S, Kim J, Park J, Butler D, Meydan C, Foox J, Bram Y, Richard SA, Epsi NJ, Agan B, Chenoweth JG, Simons MP, Tribble D, Burgess T, Dalgard C, Heise MT, Moorman NJ, Baxter VK, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Beigel K, Widjaja GA, Janssen KA, Lie T, Murdock DG, Angelin A, Soto Albrecht YE, Olali AZ, Cen Z, Dybas J, Priebe W, Emmett MR, Best SM, Kelsey Johnson M, Trovao NS, Clark KB, Zaksas V, Meller R, Grabham P, Schisler JC, Moraes-Vieira PM, Pollett S, Mason CE, Syrkin Wurtele E, Taylor D, Schwartz RE, Beheshti A, Wallace DC, Baylin SB. Topper MJ, et al. Among authors: best sm. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2401968121. doi: 10.1073/pnas.2401968121. Epub 2024 Nov 27. Proc Natl Acad Sci U S A. 2024. PMID: 39602262
Molecular diagnoses and candidate gene identification in the congenital heart disease cohorts of the 100,000 genomes project.
Hartill V, Kabir M, Best S, Shaikh Qureshi WM, Baross SL, Lord J, Yu J, Sasaki E, Needham H, Shears D, Roche M, Wall E, Cooper N, Ryan G, Eason J, Johnson R, Keavney B, Hentges KE, Johnson CA. Hartill V, et al. Among authors: best s. Eur J Hum Genet. 2024 Nov 26. doi: 10.1038/s41431-024-01744-2. Online ahead of print. Eur J Hum Genet. 2024. PMID: 39587356
Novel Macrocyclic NLRP3 Inhibitors.
Mesch S, Shannon J, Miller D, MacLeod A, Bouché L, Johnston HJ, Matthews K, Paehler A, Best S, Guba W, Alanine T, Halai R, Charge L, Garside S, Thom S, Incerti-Pradillos C, McPherson C, Carrillo J, St-Gallay S, Rigo P, Schlicht S, Hendrick AG, Lerner C, Piali L, Blaising J, Mracsko EZ, Jaeschke G, Cooper MA. Mesch S, et al. Among authors: best s. J Med Chem. 2024 Nov 25. doi: 10.1021/acs.jmedchem.4c01376. Online ahead of print. J Med Chem. 2024. PMID: 39585325
Nationwide, Couple-Based Genetic Carrier Screening.
Kirk EP, Delatycki MB, Archibald AD, Tutty E, Caruana J, Halliday JL, Lewis S, McClaren BJ, Newson AJ, Dive L, Best S, Long JC, Braithwaite J, Downes MJ, Scuffham PA, Massie J, Barlow-Stewart K, Kulkarni A, Ruscigno A, Kanga-Parabia A, Rodrigues B, Bennetts BH, Ebzery C, Hunt C, Cliffe CC, Lee C, Azmanov D, King EA, Madelli EO, Zhang F, Ho G, Danos I, Liebelt J, Fletcher J, Kennedy J, Beilby J, Emery JD, McGaughran J, Marum JE, Scarff K, Fisk K, Harrison K, Boggs K, Giameos L, Fitzgerald L, Thomas L, Burnett L, Freeman L, Harris M, Berbic M, Davis MR, Cifuentes Ochoa M, Wallis M, Wall M, Chow MTM, Ferrie MM, Pachter N, Quayum N, Lang N, Kasi Pandy P, Casella R, Allcock RJN, Ong R, Edwards S, Sundercombe S, Jelenich S, Righetti S, Lunke S, Kaur S, Stock-Myer S, Eggers S, Walker SP, Theodorou T, Catchpool T, Clinch T, Roscioli T, Hardy T, Zhu Y, Fehlberg Z, Boughtwood TF, Laing NG; Mackenzie’s Mission Investigators; Mackenzie's Mission Investigators. Kirk EP, et al. Among authors: best s. N Engl J Med. 2024 Nov 21;391(20):1877-1889. doi: 10.1056/NEJMoa2314768. N Engl J Med. 2024. PMID: 39565987
Autologous Epstein-Barr virus-specific adoptive T-cell therapy in a patient with lupus nephritis.
Ranganathan D, Leibowitz S, John GT, Neller MA, Ambalathingal GR, Beagley L, Panikkar A, Best S, Raju J, Reddiex H, Ratanjee S, Ng MSY, Smith C, Khanna R. Ranganathan D, et al. Among authors: best s. Clin Transl Immunology. 2024 Nov 19;13(11):e70015. doi: 10.1002/cti2.70015. eCollection 2024. Clin Transl Immunology. 2024. PMID: 39564002 Free PMC article.
1,012 results